2016

[20] KLB is associated with alcohol drinking, and its gene product ?-Klotho is necessary for FGF21 regulation of alcohol preference. Schumann G et al. Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):14372-14377

[19] TECRL, a new life-threatening inherited arrhythmia gene associated with overlapping clinical features of both LQTS and CPVT. Devalla HD, Gélinas R, Aburawi EH, Beqqali A, Goyette P, Freund C, Chaix MA, Tadros R, Jiang H, Le Béchec A, Monshouwer-Kloots JJ, Zwetsloot T, Kosmidis G, Latour F, Alikashani A, Hoekstra M, Schlaepfer J, Mummery CL, Stevenson B, Kutalik Z, de Vries AA, Rivard L, Wilde AA, Talajic M, Verkerk AO, Al-Gazali L, Rioux JD, Bhuiyan ZA, Passier R. EMBO Mol Med. 2016 Dec 1;8(12):1390-1408.

[18] ORMDL3 expression levels have no influence on the activity of serine palmitoyltransferase. Zhakupova A, Debeuf N, Krols M, Toussaint W, Vanhoutte L, Alecu I, Kutalik Z, Vollenweider P, Ernst D, von Eckardstein A, Lambrecht BN, Janssens S, Hornemann T. FASEB J. 2016 Dec;30(12):4289-4300.

[17] Across-cohort QC analyses of GWAS summary statistics from complex traits. Chen GB, Lee SH, Robinson MR, Trzaskowski M, Zhu ZX, Winkler TW, Day FR, Croteau-Chonka DC, Wood AR, Locke AE, Kutalik Z, Loos RJ, Frayling TM, Hirschhorn JN, Yang J, Wray NR; Genetic Investigation of Anthropometric Traits (GIANT) Consortium, Visscher PM. Eur J Hum Genet. 2016 Jan;25(1):137-146.

[16] Genome-wide analysis identifies 12 loci influencing human reproductive behavior. Barban N et al. Nat Genet. 2016 Dec;48(12):1462-1472.

[15] A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape. Ried JS, Jeff M J, Chu AY, Bragg-Gresham JL, van Dongen J, Huffman JE, Ahluwalia TS, Cadby G, Eklund N, Eriksson J, Esko T, Feitosa MF, Goel A, Gorski M, Hayward C, Heard-Costa NL, Jackson AU, Jokinen E, Kanoni S, Kristiansson K, Kutalik Z, […253 authors…], Loos RJ Nat Commun. 2016 Nov 23;7:13357.

[14] New quality measure for SNP array based CNV detection. Macé A, Tuke MA, Beckmann JS, Lin L, S J, Weedon MN, Reymond A, Kutalik ZBioinformatics. 2016 Nov 1;32(21):3298-3305.

[13] Weighted Genetic Risk Scores and Prediction of Weight Gain in Solid Organ Transplant Populations. Saigi-Morgui N, Quteineh L, Bochud PY, Crettol S, Kutalik Z, Wojtowicz A, Bibert S, Beckmann S, Mueller NJ, Binet I, van Delden C, Steiger J, Mohacsi P, Stirnimann G, Soccal PM, Pascual M, Eap CB; Swiss Transplant Cohort Study. PLoS One. 2016 Oct 27;11(10):e0164443.

[12] Genome-wide associations for birth weight and correlations with adult disease. Horikoshi M*, Beaumont RN*  et al. Nature. 2016 Sep 28;538(7624):248-252.

[11] The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Ehret GB et al. Nat Genet. 2016 Oct;48(10):1171-84.

[10] Genome-wide association study identifies 74 loci associated with educational attainment. Okbay A et al. Nature. 2016 May 11;533(7604):539-42.

[9] Tissue-specific regulatory circuits reveal variable modular perturbations across complex diseases. Marbach D, Lamparter D, Quon G, Kellis M, Kutalik Z, Bergmann S. Nat Methods. 2016 Apr;13(4):366-70.

[8] Association of genetic risk scores with body mass index in Swiss psychiatric cohorts. Saigi-Morgui N, Vandenberghe F, Delacrétaz A, Quteineh L, Gholamrezaee M, Aubry JM, von Gunten A, Kutalik Z, Conus P, Eap CB. Pharmacogenet Genomics.2016 May;26(5):208-17.

[7] Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels. Kilpeläinen TO et al. Nat Commun. 2016 Feb 1;7:10494.

[6] Impact of a cis-associated gene expression SNP on chromosome 20q11.22 on bipolar disorder susceptibility, hippocampal structure and cognitive performance. Li M, Luo XJ, Landén M, Bergen SE, Hultman CM, Li X, Zhang W, Yao YG, Zhang C, Liu J, Mattheisen M, Cichon S, Mühleisen TW, Degenhardt FA, Nöthen MM, Schulze TG, Grigoroiu-Serbanescu M, Li H, Fuller CK, Chen C, Dong Q, Chen C, Jamain S, Leboyer M, Bellivier F, Etain B, Kahn JP, Henry C, Preisig M, Kutalik Z, Castelao E, Wright A, Mitchell PB, Fullerton JM, Schofield PR, Montgomery GW, Medland SE, Gordon SD, Martin NG; MooDS Consortium; Swedish Bipolar Study Group, Rietschel M, Liu C, Kleinman JE, Hyde TM, Weinberger DR, Su B. Br J Psychiatry. 2016 Feb;208(2):128-37

[5] Fast and Rigorous Computation of Gene and Pathway Scores from SNP-Based Summary Statistics. Lamparter D, Marbach D, Rueedi R, Kutalik Z*, Bergmann S*. PLoS Comput Biol. 2016 Jan 25;12(1):e1004714.

[4] Meta-analysis of genome-wide association studies of anxiety disorders. Otowa T et al.  Mol Psychiatry. 2016 Oct;21(10):1391-9.

[3] Prevalence and Determinants of Periodic Limb Movements in the General Population. Haba-Rubio J, Marti-Soler H, Marques-Vidal P, Tobback N, Andries D, Preisig M, Waeber G, Vollenweider P, Kutalik Z, Tafti M, Heinzer R. Ann Neurol. 2016 Mar;79(3):464-74

[2] Genome-wide Association Studies Identify Genetic Loci Associated with Albuminuria in Diabetes. Teumer A et alDiabetes. 2016 Mar;65(3):803-17.

[1] Narcolepsy-Associated HLA Class I Alleles Implicate Cell-Mediated Cytotoxicity. Tafti M, Lammers GJ, Dauvilliers Y, Overeem S, Mayer G, Nowak J, Pfister C, Dubois V, Eliaou JF, Eberhard HP, Liblau R, Wierzbicka A, Geisler P, Bassetti CL, Mathis J, Lecendreux M, Khatami R, Heinzer R, Haba-Rubio J, Feketeova E, Baumann CR, Kutalik Z*, Tiercy JM*. Sleep. 2016 Mar 1;39(3):581-7.