2022

[9] A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids. Ramdas S et al. Am J Hum Genet. 2022 Aug 4;109(8):1366-1387.

[8] A cross-disorder dosage sensitivity map of the human genome. Collins RL, Glessner JT, Porcu E, Lepamets M, Brandon R, Lauricella C, Han L, Morley T, Niestroj LM, Ulirsch J, Everett S, Howrigan DP, Boone PM, Fu J, Karczewski KJ, Kellaris G, Lowther C, Lucente D, Mohajeri K, Nõukas M, Nuttle X, Samocha KE, Trinh M, Ullah F, Võsa U; Epi25 Consortium; Estonian Biobank Research Team, Hurles ME, Aradhya S, Davis EE, Finucane H, Gusella JF, Janze A, Katsanis N, Matyakhina L, Neale BM, Sanders D, Warren S, Hodge JC, Lal D, Ruderfer DM, Meck J, Mägi R, Esko T, Reymond A, Kutalik Z, Hakonarson H, Sunyaev S, Brand H, Talkowski ME. Cell. 2022 Aug 1:S0092-8674(22)00788-7.

[7] Polynomial Mendelian randomization reveals non-linear causal effects for obesity-related traits. Sulc J, Sjaarda J, Kutalik Z. HGG Adv. 2022 Jun 22;3(3):100124.

[6] Possible association of 16p11.2 copy number variation with altered lymphocyte and neutrophil counts. Giannuzzi G, Chatron N, Mannik K, Auwerx C, Pradervand S, Willemin G, Hoekzema K, Nuttle X, Chrast J, Sadler MC, Porcu E; 16p11.2 Consortium, Herault Y, Isidor B, Gilbert-Dussardier B, Eichler EE, Kutalik Z, Reymond A. NPJ Genom Med. 2022 Jun 17;7(1):38. 

[5] The Genetic Etiology of Periodic Leg Movement in Sleep. Edelson JL, Schneider LD, Amar D, Brink-Kjaer A, Cederberg KL, Kutalik Z, Hagen EW, Peppard PE, Tempaku PF, Tufik S, Evans DS, Stone K, Tranah G, Cade B, Redline S, Haba-Rubio J, Heinzer R, Marques-Vidal P, Vollenweider P, Winkelmann J, Zou J, Mignot E. Sleep. 2022 Jun 7:zsac121.

[4] Using genetic variation to disentangle the complex relationship between food intake and health outcomes. Pirastu N, McDonnell C, Grzeszkowiak EJ, Mounier N, Imamura F, Merino J, Day FR, Zheng J, Taba N, Concas MP, Repetto L, Kentistou KA, Robino A, Esko T, Joshi PK, Fischer K, Ong KK, Gaunt TR, Kutalik Z, Perry JRB, Wilson JF. PLoS Genet. 2022 Jun 2;18(6):e1010162. 

[3] Improving polygenic prediction with genetically inferred ancestry. Naret O, Kutalik Z, Hodel F, Xu ZM, Marques-Vidal P, Fellay J. HGG Adv. 2022 Apr 20;3(3):100109.

[2] From pharmacogenetics to pharmaco-omics: Milestones and future directions. Auwerx C*, Sadler MC*, Reymond A+, Kutalik Z+ HGG Adv. 2022 Mar 16;3(2):100100. doi: 10.1016/j.xhgg.2022.100100. eCollection 2022 Apr 14.

[1] The individual and global impact of copy-number variants on complex human traits. Auwerx C, Lepamets M, Sadler MC, Patxot M, Stojanov M, Baud D, Mägi R; Estonian Biobank Research Team, Porcu E, Reymond A*, Kutalik Z* Am J Hum Genet. 2022 Feb 25:S0002-9297(22)00061-1. doi: 10.1016/j.ajhg.2022.02.010.