SGG joins SIB
The group has become member of the Swiss Institute of Bioinformatics (SIB) after the voting of the SIB Foundation Council on 26 June. Further details are here.
SGG joins SIB Read MoreAuthor: Zoltan Kutalik
Zoltán nominated as Assistant Professor
In April 2013 Zoltán Kutalik was nominated as Assistant Professor of the Faculty of Biology and Medicine of the University of Lausanne. He will be working in the Statistics Unit …
Zoltán nominated as Assistant Professor Read MoreLeenaards prize 2013
The team of Pierre-Yves Bochud (CHUV-UNIL), Zoltán Kutalik (UNIL-SIB), Oscar Marchetti (CHUV-UNIL) and Christian van Delden (HUG & UNIGE) received the Leenaards Prize 2013 for their project “Host genome and …
Leenaards prize 2013 Read MoreMulti-SNP association method reveals allelic heterogeneity
There are many known examples of the allelic heterogeneity and imperfect tagging phenomena. The former one is of great importance in monogenic traits but has not yet been systematically investigated …
Multi-SNP association method reveals allelic heterogeneity Read MoreTwo novel SNPs associated with HCV-induced fibrosis progression
Only a fraction of patients with chronic HCV infection develop liver fibrosis, a process that might also be affected by genetic factors. We studied well-characterized HCV-infected patients of European descent …
Two novel SNPs associated with HCV-induced fibrosis progression Read MoreHypergenes eNOS discovery
The HYPERGENES Project investigated associations between genetic variants and essential hypertension pursuing a 2-stage study by recruiting cases and controls from extensively characterized cohorts recruited over many years in different …
Hypergenes eNOS discovery Read MoreMirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus
Underweight and obese phenotypes can both pose health risks. But whereas obesity has been associated with a number of genetic variants, little is known about the genetic basis of underweight. …
Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus Read MoreNovel method to estimate explained variance of GWAS hits reveals large fraction of the missing heritability
Genome-wide association studies (GWAS) are conducted with the promise to discover novel genetic variants associated with diverse traits. For most traits, associated markers individually explain just a modest fraction of …
Novel method to estimate explained variance of GWAS hits reveals large fraction of the missing heritability Read MoreHundreds of genomic variants are associated with human anthropometric traits
Via the CoLaus and Hypergenes cohorts our group contributed to the meta-analysis of the GIANT consortium that revealed hundreds of genetic variants associated with human height; 18 new loci for …
Hundreds of genomic variants are associated with human anthropometric traits Read MoreGenome-wide Association Study reveals new HLA-haplotype strongly protective against narcolepsy
We are involved in a Genome-wide Association Study on narcolepsy conducted by Mehdi Tafti’s Group at the University of Lausanne. In brief, we identified a haplotype in the HLA-region that …
Genome-wide Association Study reveals new HLA-haplotype strongly protective against narcolepsy Read More