2024

[12] Lipid disturbances induced by psychotropic drugs: clinical and genetic predictors for early worsening of lipid levels and new-onset dyslipidaemia in Swiss psychiatric samples. Delacrétaz A, Sadler M, Gamma F, Preisig M, Richard-Lepouriel H, von Gunten A, Conus P, Plessen KJ, Kutalik Z, Eap CB. BJPsych Open. 2024 Dec 5;10(6):e227. 

[11] Identification of rare disease genes as drivers of common diseases through tissue-specific gene regulatory networks. Bakker OB, Claringbould A, Westra HJ, Wiersma H, Boulogne F, Võsa U, Urzúa-Traslaviña CG, Mulcahy Symmons S, Zidan MMM, Sadler MC, Kutalik Z, Jonkers IH, Franke L, Deelen P. Sci Rep. 2024 Dec 4;14(1):30206.

[10] Psychotropic-induced weight gain and telomere length: results from a one-year longitudinal study and a large population-based cohort. Piras M, Lin J, Sadler MC, Ranjbar S, Grosu C, Laaboub N, Preisig M, Gamma F, Plessen KJ, von Gunten A, Conus P, Kutalik Z, Eap CB. Transl Psychiatry. 2024 Nov 15;14(1):471. 

[9] Widespread natural selection on metabolite levels in humans. Timasheva Y, Lepik K, Liska O, Papp B, Kutalik Z Genome Res. 2024 Sep 9. doi: 10.1101/gr.278756.123. 

[8] Disentangling mechanisms behind the pleiotropic effects of proximal 16p11.2 BP4-5 CNVs. Auwerx C, Moix S, Kutalik Z*, Reymond A* Am J Hum Genet. 2024 Sep 23:S0002-9297(24)00300-8.

[7] The pleiotropic spectrum of proximal 16p11.2 CNVs. Auwerx C, Kutalik Z*, Reymond A* Am J Hum Genet. 2024 Sep 23:S0002-9297(24)00301-X.

[6] Breaking down causes, consequences, and mediating effects of telomere length variation on human health. Moix S, Sadler MC, Kutalik Z*, Auwerx C* Genome Biol. 2024 May 17;25(1):125.

[5] Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits. Keaton JM et al Nat Genet. 2024 May;56(5):778-791.

[4] DNA methylation may partly explain psychotropic drug-induced metabolic side effects: results from a prospective 1-month observational study. Dubath C, Porcu E, Delacrétaz A, Grosu C, Laaboub N, Piras M, von Gunten A, Conus P, Plessen KJ, Kutalik Z, Eap CB. Clin Epigenetics. 2024 Feb 28;16(1):36

[3] PheWAS-based clustering of Mendelian Randomisation instruments reveals distinct mechanism-specific causal effects between obesity and educational attainment. Darrous L, Hemani G, Davey Smith G, Kutalik Z. Nat Commun. 2024 Feb 15;15(1):1420. 

[2] Causality-enriched epigenetic age uncouples damage and adaptation. Ying K, Liu H, Tarkhov AE, Sadler MC, Lu AT, Moqri M, Horvath S, Kutalik Z, Shen X, Gladyshev VN. Nat Aging. 2024 Jan 19. doi: 10.1038/s43587-023-00557-0.

[1] Rare copy-number variants as modulators of common disease susceptibility. Auwerx C, Jõeloo M, Sadler MC, Tesio N, Ojavee S, Clark CJ, Mägi R; Estonian Biobank Research Team; Reymond A*, Kutalik Z* Genome Med. 2024 Jan 8;16(1):5. doi: 10.1186/s13073-023-01265-5.