2017

[28] Common variants at 2q11.2, 8q21.3, and 11q13.2 are associated with major mood disorders. Xiao X, Wang L, Wang C, Yuan TF, Zhou D, Zheng F, Li L, Grigoroiu-Serbanescu M, Ikeda M, Iwata N, Takahashi A, Kamatani Y, Kubo M, Preisig M, Kutalik Z, Castelao E, Pistis G, Amin N, van Duijn CM, Forstner AJ, Strohmaier J, Hecker J, Schulze TG, Müller-Myhsok B, Reif A, Mitchell PB, Martin NG, Schofield PR, Cichon S, Nöthen MM, Chang H, Luo XJ, Fang Y, Yao YG, Zhang C, Rietschel M, Li M; Advanced Collaborative Study of Mood Disorder (COSMO) Team, MooDS Bipolar Consortium. Transl Psychiatry. 2017 Dec 11;7(12):1273.

[27] Metabomatching: Using genetic association to identify metabolites in proton NMR spectroscopy. Rueedi R, Mallol R, Raffler J, Lamparter D, Friedrich N, Vollenweider P, Waeber G, Kastenmüller G, Kutalik Z*, Bergmann S*. PLoS Comput Biol. 2017 Dec 1;13(12):e1005839.

[26] Impact of CD14 Polymorphisms on Anti-Apo A-1 (Apolipoprotein A-1) IgG-Related Coronary Artery Disease Prediction in the General Population. Antiochos P, Marques-Vidal P, Virzi J, Pagano S, Satta N, Hartley O, Montecucco F, Mach F, Kutalik Z, Waeber G, Vollenweider P, Vuilleumier N. Arterioscler Thromb Vasc Biol. 2017 Dec;37(12):2342-2349.

[25] Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity. Joshi PK, Pirastu N, Kentistou KA, Fischer K, Hofer E, Schraut KE, Clark DW, Nutile T, Barnes CLK, Timmers PRHJ, Shen X, Gandin I, McDaid AF, Hansen TF, Gordon SD, Giulianini F, Boutin TS, Abdellaoui A, Zhao W, Medina-Gomez C, Bartz TM, Trompet S, Lange LA, Raffield L, van der Spek A, Galesloot TE, Proitsi P, Yanek LR, Bielak LF, Payton A, Murgia F, Concas MP, Biino G, Tajuddin SM, Seppälä I, Amin N, Boerwinkle E, Børglum AD, Campbell A, Demerath EW, Demuth I, Faul JD, Ford I, Gialluisi A, Gögele M, Graff M, Hingorani A, Hottenga JJ, Hougaard DM, Hurme MA, Ikram MA, Jylhä M, Kuh D, Ligthart L, Lill CM, Lindenberger U, Lumley T, Mägi R, Marques-Vidal P, Medland SE, Milani L, Nagy R, Ollier WER, Peyser PA, Pramstaller PP, Ridker PM, Rivadeneira F, Ruggiero D, Saba Y, Schmidt R, Schmidt H, Slagboom PE, Smith BH, Smith JA, Sotoodehnia N, Steinhagen-Thiessen E, van Rooij FJA, Verbeek AL, Vermeulen SH, Vollenweider P, Wang Y, Werge T, Whitfield JB, Zonderman AB, Lehtimäki T, Evans MK, Pirastu M, Fuchsberger C, Bertram L, Pendleton N, Kardia SLR, Ciullo M, Becker DM, Wong A, Psaty BM, van Duijn CM, Wilson JG, Jukema JW, Kiemeney L, Uitterlinden AG, Franceschini N, North KE, Weir DR, Metspalu A, Boomsma DI, Hayward C, Chasman D, Martin NG, Sattar N, Campbell H, Esko T, Kutalik Z, Wilson JF. Nat Commun. 2017 Oct 13;8(1):910.

[24] CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits. Macé A, Tuke MA, Deelen P, Kristiansson K, Mattsson H, Nõukas M, Sapkota Y, Schick U, Porcu E, Rüeger S, McDaid AF, Porteous D, Winkler TW, Salvi E, Shrine N, Liu X, Ang WQ, Zhang W, Feitosa MF, Venturini C, van der Most PJ, Rosengren A, Wood AR, Beaumont RN, Jones SE, Ruth KS, Yaghootkar H, Tyrrell J, Havulinna AS, Boers H, Mägi R, Kriebel J, Müller-Nurasyid M, Perola M, Nieminen M, Lokki ML, Kähönen M, Viikari JS, Geller F, Lahti J, Palotie A, Koponen P, Lundqvist A, Rissanen H, Bottinger EP, Afaq S, Wojczynski MK, Lenzini P, Nolte IM, Sparsø T, Schupf N, Christensen K, Perls TT, Newman AB, Werge T, Snieder H, Spector TD, Chambers JC, Koskinen S, Melbye M, Raitakari OT, Lehtimäki T, Tobin MD, Wain LV, Sinisalo J, Peters A, Meitinger T, Martin NG, Wray NR, Montgomery GW, Medland SE, Swertz MA, Vartiainen E, Borodulin K, Männistö S, Murray A, Bochud M, Jacquemont S, Rivadeneira F, Hansen TF, Oldehinkel AJ, Mangino M, Province MA, Deloukas P, Kooner JS, Freathy RM, Pennell C, Feenstra B, Strachan DP, Lettre G, Hirschhorn J, Cusi D, Heid IM, Hayward C, Männik K, Beckmann JS, Loos RJF, Nyholt DR, Metspalu A, Eriksson JG, Weedon MN, Salomaa V, Franke L, Reymond A, Frayling TM*, Kutalik Z* Nat Commun. 2017 Sep 29;8(1):744

[23] C-reactive protein upregulates the whole blood expression of CD59 – an integrative analysis. Lepik K, Annilo T, Kukuškina V, Kisand K, Kutalik Z*, Peterson P*, Peterson H*; eQTLGen Consortium. PLoS Comput Biol. 2017 Sep 18;13(9):e1005766.

[22] Risk prediction of developing venous thrombosis in combined oral contraceptive users. McDaid A, Logette E, Buchillier V, Muriset M, Suchon P, Pache TD, Tanackovic G, Kutalik Z, Michaud J. PLoS One. 2017 Jul 27;12(7):e0182041.

[21] Approaches to detect genetic effects that differ between two strata in genome-wide meta-analyses: Recommendations based on a systematic evaluation. Winkler TW, Justice AE, Cupples LA, Kronenberg F, Kutalik Z*, Heid IM*; GIANT consortium. PLoS One. 2017 Jul 27;12(7):e0181038.

[20] Bayesian association scan reveals loci associated with human lifespan and linked biomarkers. McDaid AF, Joshi PK, Porcu E, Komljenovic A, Li H, Sorrentino V, Litovchenko M, Bevers RPJ, Rüeger S, Reymond A, Bochud M, Deplancke B, Williams RW, Robinson-Rechavi M, Paccaud F, Rousson V, Auwerx J, Wilson JF, Kutalik Z. Nat Commun. 2017 Jul 27;8:15842.

[19] Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. Zillikens MC, Demissie S, Hsu YH, Yerges-Armstrong LM, Chou WC, Stolk L, Livshits G, Broer L, Johnson T, Koller DL, Kutalik Z, […], Kiel DP. Nat Commun. 2017 Jul 19;8(1):80.

[18] Interaction between the FTO gene, body mass index and depression: meta-analysis of 13701 individuals. Rivera M et al. Br J Psychiatry. 2017 Aug;211(2):70-76.

[16] 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function. Gorski M, et al. Sci Rep. 2017 Apr 28;7:45040.

[15] Genome-wide physical activity interactions in adiposity – A meta-analysis of 200,452 adults. Graff M, Scott RA, Justice AE, Young KL, Feitosa MF, Barata L, Winkler TW, Chu AY, Mahajan A, Hadley D, Xue L, Workalemahu T, Heard-Costa NL, den Hoed M, Ahluwalia TS, Qi Q, Ngwa JS, Renström F, Quaye L, Eicher JD, Hayes JE, Cornelis M, Kutalik Z, […252 authors…], Borecki IB, Franks PW, North KE, Cupples LA, Loos RJF, Kilpeläinen TO. PLoS Genet. 2017 Apr 27;13(4):e1006528.

[14] Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Justice AE,* Winkler TW*, Feitosa MF, Graff M, Fisher VA, Young K, Barata L, Deng X, Czajkowski J, Hadley D, Ngwa JS, Ahluwalia TS, Chu AY, Heard-Costa NL, Lim E, Perez J, Eicher JD, Kutalik Z, […296 authors…], Borecki IB, North KE, Cupples LA. Nat Commun. 2017 Apr 26;8:14977.

[13] Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk. Day FR et al. Nat Genet. 2017 Jun;49(6):834-841.

[12] SQC: Secure Quality Control for Meta-Analysis of Genome-Wide Association Studies. Huang Z, Lin H, Fellay J, Kutalik Z, Hubaux JP. Bioinformatics. 2017 Aug 1;33(15):2273-2280.

[11] NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality Böger CA et al.  J Am Soc Nephrol. 2017 Aug;28(8):2311-2321.

[10] Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness. Heilmann-Heimbach S, Herold C, Hochfeld LM, Hillmer AM, Nyholt DR, Hecker J, Javed A, Chew EG, Pechlivanis S, Drichel D, Heng XT, Del Rosario RC, Fier HL, Paus R, Rueedi R, Galesloot TE, Moebus S, Anhalt T, Prabhakar S, Li R, Kanoni S, Papanikolaou G, Kutalik Z, Deloukas P, Philpott MP, Waeber G, Spector TD, Vollenweider P, Kiemeney LA, Dedoussis G, Richards JB, Nothnagel M, Martin NG, Becker T, Hinds DA, Nöthen MM. Nat Commun. 2017 Mar 8;8:14694.

[9] A Systematic Review and Meta-Analysis of HCV Clearance. Gauthiez E, Habfast-Robertson I, Rüeger S, Kutalik Z, Aubert V, Berg T, Cerny A, Gorgievski M, George J, Heim MH, Malinverni R, Moradpour D, Müllhaupt B, Negro F, Semela D, Semmo N, Villard J, Bibert S, Bochud PY; Swiss Hepatitis C Cohort Study. Liver Int. 2017 Oct;37(10):1431-1445.

[8] cis-Acting Complex-Trait-Associated lincRNA Expression Correlates with Modulation of Chromosomal Architecture. Tan JY, Smith AA, Ferreira da Silva M, Matthey-Doret C, Rueedi R, Sönmez R, Ding D, Kutalik Z, Bergmann S, Marques AC. Cell Rep. 2017 Feb 28;18(9):2280-2288.

[7] Rare and low-frequency coding variants alter human adult height. Marouli E, Graff M, Medina-Gomez C, Lo KS, Wood AR, Kjaer TR, Fine RS, Lu Y, Schurmann C, Highland HM, Rüeger S, Thorleifsson G, Justice AE, Lamparter D, […351 authors…], Kutalik Z*, Rivadeneira F*, Loos RJ*, Frayling TM*, Hirschhorn JN*, Deloukas P*, Lettre G.* Nature. 2017 Feb 9;542(7640):186-190.

[6] Genome-Wide Association between Transcription Factor Expression and Chromatin Accessibility Reveals Regulators of Chromatin Accessibility. Lamparter D, Marbach D, Rueedi R, Bergmann S, Kutalik Z. PLoS Comput Biol. 2017 Jan 24;13(1):e1005311.

[5] Gene-obesogenic environment interactions in the UK Biobank study. Tyrrell J, Wood AR, Ames RM, Yaghootkar H, Beaumont RN, Jones SE, Tuke MA, Ruth KS, Freathy RM, Davey Smith G, Joost S, Guessous I, Murray A, Strachan DP, Kutalik Z, Weedon MN, Frayling TM. Int J Epidemiol.2017 Apr 1;46(2):559-575.

[4] Quantifying the extent to which index event biases influence large genetic association studies. Yaghootkar H, Bancks MP, Jones SE, McDaid A, Beaumont R, Donnelly L, Wood AR, Campbell A, Tyrrell J, Hocking LJ, Tuke MA, Ruth KS, Pearson ER, Murray A, Freathy RM, Munroe PB, Hayward C, Palmer C, Weedon MN, Pankow JS, Frayling TM*, Kutalik Z*. Hum Mol Genet. 2017 Mar 1;26(5):1018-1030

[3] An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype. Direk N et al. Biol Psychiatry. 2017 Sep 1;82(5):322-329.

[2] Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Power RA, Tansey KE, Buttenschøn HN, Cohen-Woods S, Bigdeli T, Hall LS, Kutalik Z, […69 authors…], Breen G, Lewis CM. Biol Psychiatry. 2017 Feb 15;81(4):325-335

[1] CRTC2 polymorphism as a risk factor for the incidence of metabolic syndrome in patients with solid organ transplantation. Quteineh L, Bochud PY, Golshayan D, Crettol S, Venetz JP, Manuel O, Kutalik Z, Treyer A, Lehmann R, Mueller NJ, Binet I, van Delden C, Steiger J, Mohacsi P, Dufour JF, Soccal PM, Pascual M, Eap CB; and The Swiss Transplant Cohort Study. Pharmacogenomics J. 2017 Jan;17(1):69-75.