Website of the Statistical Genetics Group
The HYPERGENES Project investigated associations between genetic variants and essential hypertension pursuing a 2-stage study by recruiting cases and controls from extensively characterized cohorts recruited over many years in different …
Hypergenes eNOS discovery Read MoreUnderweight and obese phenotypes can both pose health risks. But whereas obesity has been associated with a number of genetic variants, little is known about the genetic basis of underweight. …
Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus Read MoreGenome-wide association studies (GWAS) are conducted with the promise to discover novel genetic variants associated with diverse traits. For most traits, associated markers individually explain just a modest fraction of …
Novel method to estimate explained variance of GWAS hits reveals large fraction of the missing heritability Read MoreVia the CoLaus and Hypergenes cohorts our group contributed to the meta-analysis of the GIANT consortium that revealed hundreds of genetic variants associated with human height; 18 new loci for …
Hundreds of genomic variants are associated with human anthropometric traits Read MoreWe are involved in a Genome-wide Association Study on narcolepsy conducted by Mehdi Tafti’s Group at the University of Lausanne. In brief, we identified a haplotype in the HLA-region that …
Genome-wide Association Study reveals new HLA-haplotype strongly protective against narcolepsy Read More