Bayesian GWAS: Lifespan

The answer to how long each of us will live is partly encoded in our genome. We have identified 16 genetic markers associated with a decreased lifespan, including 14 new to science. This is the largest set of markers of lifespan uncovered to date. About 10% of the population carries some configurations of these markers that shorten their life by over a year compared with the population average. Spearheaded by us in collaboration with scientists from the SIB Swiss Institute of Bioinformatics, the University of Lausanne and the EPFL, the study provides a powerful computational framework to uncover the genetics of our time of death, and ultimately of any disease. The study was published on 27 July in Nature Communications.

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