2024
Concepcion Manzano, Kevin W. Morimoto, Lidor Shaar-Moshe, G. Alex Mason, Alex Cantó-Pastor, Mona Gouran, Damien De Bellis, Robertas Ursache, Kaisa Kajala, Neelima Sinha, Julia Bailey-Serres, Niko Geldner, J. Carlos del Pozo & Siobhan M. Brady. Regulation and function of a polarly localized lignin barrier in the exodermis. Nat. Plants (2024). https://doi.org/10.1038/s41477-024-01864-z
Yan Ma, Isabelle Flückiger, Jade Nicolet, Jia Pang, Joe B. Dickinson, Damien De Bellis, Aurélia Emonet, Satoshi Fujita and Niko Geldner. Comparisons of two receptor-MAPK pathways in a single cell-type reveal mechanisms of signalling specificity. Nat. Plants (2024). https://doi.org/10.1038/s41477-024-01768-y
Kay Gully, Alice Berhin, Damien De Bellis, Cornelia Herrfurth, Ivo Feussner and Christiane Nawrath. The GPAT4/6/8 clade functions in Arabidopsis root suberization nonredundantly with the GPAT5/7 clade required for suberin lamellae. PNAS first published May 13, 2024. 121 (21) e2314570121 https://doi.org/10.1073/pnas.2314570121
Toullec G, Rädecker N, Pogoreutz C, Banc-Prandi G, Escrig S, Genoud C, Olmos CM, Spangenberg J, Meibom A. Host starvation and in hospite degradation of algal symbionts shape the heat stress response of the Cassiopea-Symbiodiniaceae symbiosis. Microbiome. 2024 Feb 29;12(1):42. doi: 10.1186/s40168-023-01738-0. PMID: 38424629.
Andrew Quinn, Yassine El Chazli, Stéphane Escrig, Jean Daraspe, Nicolas Neuschwander, Aoife McNally, Christel Genoud, Anders Meibom & Philipp Engel. Host-derived organic acids enable gut colonization of the honey bee symbiont Snodgrassella alvi. Nat Microbiol (2024). https://doi.org/10.1038/s41564-023-01572-y
Alex Cantó-Pastor, Kaisa Kajala, Lidor Shaar-Moshe, Concepción Manzano, Prakash Timilsena, Damien De Bellis, Sharon Gray, Julia Holbein, He Yang, Sana Mohammad, Niba Nirmal, Kiran Suresh, Robertas Ursache, G. Alex Mason, Mona Gouran, Donnelly A. West, Alexander T. Borowsky, Kenneth A. Shackel, Neelima Sinha, Julia Bailey-Serres, Niko Geldner, Song Li, Rochus Benni Franke & Siobhan M. Brady.A suberized exodermis is required for tomato drought tolerance. Nat. Plants(2024). https://doi.org/10.1038/s41477-023-01567-x.
2023
Ganesh M. Nawkar, Martina Legris, Anupama Goyal, Emanuel Schmid-Siegert, Jérémy Fleury, Antonio Mucciolo, Damien De Bellis, Martine Trevisan, Andreas Schueler and Christian Fankhauser. Air channels create a directional light signal to regulate hypocotyl phototropism. Science 382, 935-940 (2023).DOI:10.1126/science.adh9384
Steven Moussu, Hyun Kyung Lee, Kalina T. Hass, Caroline Broyart, Ursina Rathgeb, Damien De Bellis, Thomas Levasseur, Sébastjen Schoenaers, Gorka S. Fernandez, Ueli Grossniklaus, Estelle Bonnin, Eric Hosy, Kris Vissenberg, Niko Geldner, Bernard Cathala, Herman Höfte, Julia Santiago. Plant cell wall patterning and expansion mediated by protein-peptide-polysaccharide interactions. Science 382,719-725(2023).DOI:10.1126/science.adi4720
Vérièpe-Salerno J, Podavini S, Long MJC, Kolotuev I, Cuendet M, Thome M. MALT-1 shortens lifespan by inhibiting autophagy in the intestine of C. elegans. Autophagy Rep. 2023 Nov 9;2(1):2277584. doi: 10.1080/27694127.2023.2277584. PMID: 38510643; PMCID: PMC7615756.
Fung W, Tan TM, Kolotuev I, Heiman MG. A sex-specific switch in a single glial cell patterns the apical extracellular matrix. Curr Biol. 2023 Oct 9;33(19):4174-4186.e7. doi: 10.1016/j.cub.2023.08.046. Epub 2023 Sep 13. PMID: 37708887.
Serir RH, Deliot A, Kizilyaprak C, Daraspe J, Walczak C, Canini F, Leleu A, Marco S, Ronzon F, Messaoudi C. SEM3De: image restoration for FIB-SEM. Bioinform Adv. 2023 Sep 6;3(1):vbad119. doi: 10.1093/bioadv/vbad119. PMID: 37745005; PMCID: PMC10516526.
Kolotuev I. Work smart, not hard: How array tomography can help increase the ultrastructure data output. J Microsc. 2023 Aug 25. doi: 10.1111/jmi.13217. Epub ahead of print. PMID: 37626455.
Jiao W, Chatton JY, Genoud C. Mitochondria morphometry in 3D datasets obtained from mouse brains with serial block-face scanning electron microscopy. Methods Cell Biol. 2023;177:197-211. doi: 10.1016/bs.mcb.2023.01.021. Epub 2023 Mar 21. PMID: 37451767.
Peddie CJ, Genoud C, Kreshuk A, Meechan K, Micheva KD, Narayan K, Pape C, Parton RG, Schieber NL, Schwab Y, Titze B, Verkade P, Aubrey A, Collinson LM. Volume electron microscopy. Nat Rev Methods Primers. 2022 Jul 7;2:51. doi: 10.1038/s43586-022-00131-9. PMID: 37409324; PMCID: PMC7614724.
Olive M, Daraspe J, Genoud C, Kohn T. Uptake without inactivation of human adenovirus type 2 by Tetrahymena pyriformis ciliates. Environ Sci Process Impacts. 2023 Jun 28. doi: 10.1039/d3em00116d. Epub ahead of print. PMID: 37376996.
Anders Meibom, Florent Plane, Tian Cheng, Gilles Grandjean, Olivier Haldimann, Stephane Escrig, Louise Jensen, Jean Daraspe, Antonio Mucciolo, Damien De Bellis, Nils Rädecker, Cristina Martin-Olmos, Christel Genoud and Arnaud Comment. Correlated cryo-SEM and CryoNanoSIMS imaging of biological tissue. BMC Biol 21, 126 (2023). https://doi.org/10.1186/s12915-023-01623-0
Galenza A, Moreno-Roman P, Su YH, Acosta-Alvarez L, Debec A, Guichet A, Knapp JM, Kizilyaprak C, Humbel BM, Kolotuev I, O’Brien LE. Basal stem cell progeny establish their apical surface in a junctional niche during turnover of an adult barrier epithelium. Nat Cell Biol. 2023 Mar 30. doi: 10.1038/s41556-023-01116-w. Epub ahead of print. PMID: 36997641.
Barbosa ICR, De Bellis D, Flückiger I, Bellani E, Grangé-Guerment M, Hématy K, Geldner N. Directed growth and fusion of membrane-wall microdomains requires CASP-mediated inhibition and displacement of secretory foci. Nat Commun. 2023 Mar 23;14(1):1626. doi: 10.1038/s41467-023-37265-7. PMID: 36959183; PMCID: PMC10036488.
Ganeva I, Lim K, Boulanger J, Hoffmann PC, Muriel O, Borgeaud AC, Hagen WJH, Savage DB, Kukulski W. The architecture of Cidec-mediated interfaces between lipid droplets. Cell Rep. 2023 Feb 15;42(2):112107. doi: 10.1016/j.celrep.2023.112107. Epub ahead of print. PMID: 36800289.
Ballmer D, Tardat M, Ortiz R, Graff-Meyer A, Ozonov EA, Genoud C, Peters AH, Fanourgakis G. HP1 proteins regulate nucleolar structure and function by secluding pericentromeric constitutive heterochromatin. Nucleic Acids Res. 2023 Jan 11;51(1):117-143. doi: 10.1093/nar/gkac1159. PMID: 36533441; PMCID: PMC9841413.
Saponara E, Penno C, Orsini V, Wang ZY, Fischer A, Aebi A, Matadamas-Guzman ML, Brun V, Fischer B, Brousseau M, O’Donnell P, Turner J, Graff Meyer A, Bollepalli L, d’Ario G, Roma G, Carbone W, Annunziato S, Obrecht M, Beckmann N, Saravanan C, Osmont A, Tropberger P, Richards SM, Genoud C, Ley S, Ksiazek I, Nigsch F, Terracciano LM, Schadt HS, Bouwmeester T, Tchorz JS, Ruffner H. Loss of Hepatic Leucine-Rich Repeat-Containing G-Protein Coupled Receptors 4 and 5 Promotes Nonalcoholic Fatty Liver Disease. Am J Pathol. 2023 Feb;193(2):161-181. doi: 10.1016/j.ajpath.2022.10.008. Epub 2022 Nov 18. PMID: 36410420.
2022
Mühlethaler-Mottet A, Uccella S, Marchiori D, La Rosa S, Daraspe J, Balmas Bourloud K, Beck Popovic M, Eugster PJ, Grouzmann E, Abid K. Low number of neurosecretory vesicles in neuroblastoma impairs massive catecholamine release and prevents hypertension. Front Endocrinol (Lausanne). 2022 Dec 1;13:1027856. doi: 10.3389/fendo.2022.1027856. PMID: 36531507; PMCID: PMC9751011.
Billault-Chaumartin I, Muriel O, Michon L, Martin SG. Condensation of the fusion focus by the intrinsically disordered region of the formin Fus1 is essential for cell-cell fusion. Curr Biol. 2022 Nov 7;32(21):4752-4761.e10. doi: 10.1016/j.cub.2022.09.026. Epub 2022 Oct 5. PMID: 36202103; PMCID: PMC9671092.
Ktena N, Kaplanis SI, Kolotuev I, Georgilis A, Kallergi E, Stavroulaki V, Nikoletopoulou V, Savvaki M, Karagogeos D. Autophagic degradation of CNS myelin maintains axon integrity. Cell Stress. 2022 Nov 21;6(12):93-107. doi: 10.15698/cst2022.12.274. PMID: 36478958; PMCID: PMC9707329.
Munoz O, Banga R, Schelling R, Procopio FA, Mastrangelo A, Nortier P, Ohmiti K, Daraspe J, Cavassini M, Fenwick C, Perez L, Perreau M. Active PD-L1 incorporation within HIV virions functionally impairs T follicular helper cells. PLoS Pathog. 2022 Jul 5;18(7):e1010673. doi: 10.1371/journal.ppat.1010673. Epub ahead of print. PMID: 35788752.
Jiao W, Spreemann G, Ruchti E, Banerjee S, Vernon S, Shi Y, Stowers RS, Hess K, McCabe BD. Intact Drosophila central nervous system cellular quantitation reveals sexual dimorphism. Elife. 2022 Jul 8;11:e74968. doi: 10.7554/eLife.74968. PMID: 35801638; PMCID: PMC9270032.
Wai CH, Jin J, Cyrklaff M, Genoud C, Funaya C, Sattler J, Maceski A, Meier S, Heiland S, Lanzer M, Frischknecht F, Kuhle J, Bendszus M, Hoffmann A. Neurofilament light chain plasma levels are associated with area of brain damage in experimental cerebral malaria. Sci Rep. 2022 Jun 24;12(1):10726. doi: 10.1038/s41598-022-14291-x. PMID: 35750882; PMCID: PMC9232608.
McCallin S, Menzi C, Lassen S, Daraspe J, Oechslin F, Moreillon P. Antibiotic Exposure Leads to Reduced Phage Susceptibility in Vancomycin Intermediate Staphylococcus aureus (VISA). Antimicrob Agents Chemother. 2022 Jun 16:e0224721. doi: 10.1128/aac.02247-21. Epub ahead of print. PMID: 35708333.
Santella A, Kolotuev I, Kizilyaprak C, Bao Z. Cross-modality synthesis of EM time series and live fluorescence imaging. Elife. 2022 Jun 6;11:e77918. doi: 10.7554/eLife.77918. PMID: 35666127; PMCID: PMC9213002.
Damien De Bellis, Lothar Kalmbach, Peter Marhavy, Jean Daraspe, Niko Geldner, Marie Barberon. Extracellular vesiculo-tubular structures associated with suberin deposition in plant cell walls. Nat Commun 13, 1489 (2022). https://doi.org/10.1038/s41467-022-29110-0
Ansermet C, Centeno G, Pradervand S, Harmacek D, Garcia A, Daraspe J, Kocherlakota S, Baes M, Bignon Y, Firsov D. Renal tubular peroxisomes are dispensable for normal kidney function. JCI Insight. 2022 Feb 22;7(4):e155836. doi: 10.1172/jci.insight.155836. PMID: 35191396.
Kian Hématy, Damien De Bellis, Xin Wang, Ari Pekka Mähönen, Niko Geldner. Analysis of exocyst function in endodermis reveals its widespread contribution and specificity of action. Plant Physiology, 2022;, kiac019, https://doi.org/10.1093/plphys/kiac019
Andreas Kolbeck, Peter Marhavý, Damien De Bellis, Baohai Li, Takehiro Kamiya, Toru Fujiwara, Lothar Kalmbach and Niko Geldner. CASP microdomain formation requires cross cell wall stabilization of domains and non-cell autonomous action of LOTR1.eLife 2022;11:e69602 DOI: 10.7554/eLife.69602?
Philippe Glenn, De Bellis Damien, Rose Jocelyn K. C., Nawrath Christiane. Trafficking Processes and Secretion Pathways Underlying the Formation of Plant Cuticles. Frontiers in Plant Science 12, 2022
2021
Romanova DY, Varoqueaux F, Daraspe J, Nikitin MA, Eitel M, Fasshauer D, Moroz LL. Hidden cell diversity in Placozoa: ultrastructural insights from Hoilungia hongkongensis. Cell Tissue Res. 2021 Sep;385(3):623-637. doi: 10.1007/s00441-021-03459-y. Epub 2021 Apr 19. PMID: 33876313; PMCID: PMC8523601.
Vergara HM, Pape C, Meechan KI, Zinchenko V, Genoud C, Wanner AA, Mutemi KN, Titze B, Templin RM, Bertucci PY, Simakov O, Durichen W, Machado P, Savage EL, Schermelleh L, Schwab Y, Friedrich RW, Kreshuk A, Tischer C, Arendt D Cell 2021 Aug 7
Montavon T, Shukeir N, Erikson G, Engist B, Onishi-Seebacher M, Ryan D, Musa Y, Mittler G, Meyer AG, Genoud C, Jenuwein T. Complete loss of H3K9 methylation dissolves mouse heterochromatin organization. Nat Commun. 2021 Jul 16;12(1):4359. doi: 10.1038/s41467-021-24532-8. PMID: 34272378; PMCID: PMC8285382
Franke T, Kolotuev I. Array Tomography Workflow for the Targeted Acquisition of Volume Information using Scanning Electron Microscopy. J Vis Exp. 2021 Jul 15;(173). doi: 10.3791/61847. PMID: 34338674.
Rohrbach A, Caron E, Dali R, Brunner M, Pasquettaz R, Kolotuev I, Santoni F, Thorens B, Langlet F. Ablation of glucokinase-expressing tanycytes impacts energy balance and increases adiposity in mice. Mol Metab. 2021 Jul 26:101311. doi: 10.1016/j.molmet.2021.101311. Epub ahead of print. PMID: 34325016
Romanova DY, Varoqueaux F, Daraspe J, Nikitin MA, Eitel M, Fasshauer D, Moroz LL. Hidden cell diversity in Placozoa: ultrastructural insights from Hoilungia hongkongensis. Cell Tissue Res. 2021 Apr 19. doi: 10.1007/s00441-021-03459-y. Epub ahead of print. PMID: 33876313
Carolina Elejalde-Palmett, Ignacio Martinez San Segundo, Imène Garroum, Laurence Charrier, Damien De Bellis, Antonio Mucciolo, Aurore Guerault, Jie Liu, Viktoria Zeisler-Dieh, Asaph Aharoni, Lukas Schreiber, Bénédicte Bakan, Mads H. Clausen, Markus Geisler, Christiane Nawrath. ABCG transporters export cutin precursors for the formation of the plant cuticle. Current Biology, March 2021 https://www.sciencedirect.com/science/article/pii/S0960982221003006?dgcid=coauthor
Robertas Ursache, Cristovāo De Jesus Vieira Teixeira, Valérie Dénervaud Tendon, Kay Gully, Damien De Bellis, Emanuel Schmid-Siegert, Tonni Grube Andersen, Vinay Shekhar, Sandra Calderon, Sylvain Pradervand, Christiane Nawrath, Niko Geldner & Joop E. M. Vermeer.
GDSL-domain proteins have key roles in suberin polymerization and degradation. Nature Plants, 08 March 2021. https://doi.org/10.1038/s41477-021-00862-9
Kato M, Kolotuev I, Cunha A, Gharib S, Sternberg PW. Extrasynaptic acetylcholine signaling through a muscarinic receptor regulates cell migration. Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e1904338118. doi: 10.1073/pnas.1904338118. PMID: 33361149; PMCID: PMC7817160.
2020
Nga N T Nguyen, Joaquin Clua, Pallavi V Vetal, Dominique Jacques Vuarambon, Damien de Bellis, Marjorie Pervent, Marc Lepetit, Michael Udvardi, Alexander J Valentine, Yves Poirier.
PHO1 family members transport phosphate from infected nodule cells to bacteroids in Medicago truncatula. Plant Physiology, 25 November 2020
https://academic.oup.com/plphys/advance-article/doi/10.1093/plphys/kiaa016/6003068
Stephanie K Cohen, Marie-Stéphanie Aschtgen, Jonathan B Lynch, Sabrina Koehler, Fangmin Chen, Stéphane Escrig, Jean Daraspe, Edward G Ruby, Anders Meibom, Margaret McFall-Ngai.
Tracking the cargo of extracellular symbionts into host tissues with correlated electron microscopy and nanoscale secondary ion mass spectrometry imaging. Cellular Microbiology 2020 Apr;22(4):e13177
DOI: 10.1111/cmi.13177
Nelson Rojas-Murcia, Kian Hématy, Yuree Lee, Aurélia Emonet, Robertas Ursache, Satoshi Fujita, Damien De Bellis, and Niko Geldner.
High-order mutants reveal an essential requirement for peroxidases but not laccases in Casparian strip lignification. PNAS first published November 2, 2020.
https://doi.org/10.1073/pnas.2012728117
Asier Ullate-Agote, Ingrid Burgelin, Adrien Debry, Carine Langrez, Florent Montange, Rodrigue Peraldi, Jean Daraspe, Henrik Kaessmann, Michel C. Milinkovitch, and Athanasia C. Tzika. Genome mapping of a LYST mutation in corn snakes indicates that vertebrate chromatophore vesicles are lysosome-related organelles. PNAS October 20, 2020 117 (42) 26307-26317.
https://doi.org/10.1073/pnas.2003724117
Mikhail Nikolaev, Olga Mitrofanova, Nicolas Broguiere, Sara Geraldo, Devanjali Dutta, Yoji Tabata, Bilge Elci, Nathalie Brandenberg, Irina Kolotuev, Nikolce Gjorevski, Hans Clevers, Matthias P Lutolf. Homeostatic mini-intestines through scaffold-guided organoid morphogenesis. Nature. 2020 Sep 16. PMID: 32939089
DOI: 10.1038/s41586-020-2724-8
Pasquettaz R, Kolotuev I, Rohrbach A, Gouelle C, Pellerin L, Langlet F. Peculiar protrusions along tanycyte processes face diverse neural and nonneural cell types in the hypothalamic parenchyma. J Comp Neurol. 2020 Jun 8. PMID: 32515035
doi: 10.1002/cne.24965
G. Lê‐Bury, C. Deschamps, C. Kizilyaprak, W. Blanchard, J. Daraspe, A. Dumas, M.A. Gordon, J.C.D. Hinton, B.M. Humbel, F. Niedergang. Increased intracellular survival of Salmonella Typhimurium ST313 in HIV‐1‐infected primary human macrophages is not associated with Salmonella hijacking the HIV compartment. Biology of the Cell, Volume 112, Issue 3, Pages 92-101. March 2020
https://doi.org/10.1111/boc.201900055
Satoshi Fujita, Damien De Bellis, Kai H Edel, Philipp Köster, Tonni Grube Andersen, Emanuel Schmid‐Siegert, Valérie Dénervaud Tendon, Alexandre Pfister, Peter Marhavý, Robertas Ursache, Verónica G Doblas, Marie Barberon, Jean Daraspe, Audrey Creff, Gwyneth Ingram, Jörg Kudla, Niko Geldner. SCHENGEN receptor module drives localized ROS production and lignification in plant roots. The EMBO Journal (2020)39: e103894
https://doi.org/10.15252/embj.2019103894
2019
Mumbauer S, Pascual J, Kolotuev I, Hamaratoglu F. Ferritin heavy chain protects the developing wing from reactive oxygen species and ferroptosis. PLoS Genet. 2019 Sep 30;15(9):e1008396.
doi: 10.1371/journal.pgen.1008396
Anna Keppner, Darko Maric, Chloé Sergi, Camille Ansermet, Damien De Bellis, Denise V. Kratschmar, Jérémie Canonica, Petra Klusonova, Robert A. Fenton, Alex Odermatt, Gilles Crambert, David Hoogewijs & Edith Hummler. Deletion of the serine protease CAP2/Tmprss4 leads to dysregulated renal water handling upon dietary potassium depletion. Scientific Reports volume 9, Article number: 19540 (2019)
https://doi.org/10.1038/s41598-019-55995-x
Narasimha S, Nagornov KO, Menin L, Mucciolo A, Rohwedder A, Humbel BM, Stevens M, Thum AS, Tsybin YO, Vijendravarma RK. Drosophila melanogaster cloak their eggs with pheromones, which prevents cannibalism. PLoS Biol. 2019 Jan 10;17(1):e2006012
https://doi.org/10.1371/journal.pbio.2006012
Kolotuev I, Micheva KD, Can Correlative Microscopy Ever Be Easy? An Array Tomography Viewpoint – Correlative Imaging – Wiley Online Library
Caroline Kizilyaprak, Damien De Bellis, Willy Blanchard, Jean Daraspe, Bruno M. Humbel. FIB-SEM Tomography of Biological Samples: Explore the Life in 3D. Chapter 26 in the following book: Biological Field Emission Scanning Electron Microscopy, I. Book Author(s): Roland A. Fleck, Bruno M. Humbel. 15 February 2019
https://doi.org/10.1002/9781118663233.ch26
Low IIC, Williams CR, Chong MK, McLachlan IG, Wierbowski BM, Kolotuev I, Heiman MG. Morphogenesis of neurons and glia within an epithelium.
Development, 2019 Feb 20;146(4). DOI:10.1242/dev.171124
https://doi.org/10.1242/dev.171124
2018
Lee KY, Green RA, Gutierrez E, Gomez-Cavazos JS, Kolotuev I, Wang S, Desai A, Groisman A, Oegema K. CYK-4 functions independently of its centralspindlin partner ZEN-4 to cellularize oocytes in germline syncytia. Elife. 2018 Jul 10;7
https://doi.org/10.7554/eLife.36919
Kizilyaprak C, Stierhof YD, Humbel BM. Volume microscopy in biology: FIB-SEM tomography. Tissue Cell. 2018 Sep 26. pii: S0040-8166(18)30262-3.
https://doi.org/10.1016/j.tice.2018.09.006
Eitel M, Francis WR, Varoqueaux F, Daraspe J, Osigus HJ, Krebs S, Vargas S, Blum H, Williams GA, Schierwater B, Wörheide G. Comparative genomics and the nature of placozoan species. PLoS Biol. 2018 Jul 31;16(7):e2005359
https://doi.org/10.1371/journal.pbio.2005359
Burel A, Lavault MT, Chevalier C, Gnaegi H, Prigent S, Mucciolo A, Dutertre S, Humbel BM, Guillaudeux T, Kolotuev I. 2018. A targeted 3D EM and correlative microscopy method using SEM array tomography. Development. 2018 Jun 21;145(12). pii: dev160879. doi: 10.1242/dev.160879.
https://www.ncbi.nlm.nih.gov/pubmed/29802150
Daniel E, Daudé M, Kolotuev I, Charish K, Auld V, Le Borgne R. 2018. Coordination of Septate Junctions Assembly and Completion of Cytokinesis in Proliferative Epithelial Tissues. Current Biology. 2018 May 7;28(9):1380-1391.e4. doi: 10.1016/j.cub.2018.03.034. Epub 2018 Apr 26.
https://www.ncbi.nlm.nih.gov/pubmed/29706514
2017
Pyakurel A, Balmer D, Saba-El-Leil MK, Kizilyaprak C, Daraspe J, Humbel BM, Voisin L, Le YZ, von Lintig J, Meloched S, Roduit R. 2017. Loss of extracellular signal-regulated kinase 1/2 in the retinal pigment epithelium leads to RPE65 decrease and retinal degeneration. Mol Cell Biol, 37, e00295-17.
http://mcb.asm.org/content/37/24/e00295-17.long
Kalmbach L, Hématy K, De Bellis D, Barberon M, Fujita S, Ursache R, Daraspe J, Geldner N. 2017. Transient cell-specific EXO70A1 activity in the CASP domain and Casparian strip localization. Nature Plants 3, Article number: 17058
doi:10.1038/nplants.2017.58
https://www.nature.com/articles/nplants201758
Hoang TV, Kizilyaprak C, Spehner D, Humbel BM, Schultz P. 2017. Automatic segmentation of high pressure frozen and freeze-substituted mouse retina nuclei from FIB-SEM tomograms. J Struct Biol, 123-134.
http://dx.doi.org/10.1016/j.jsb.2016.10.005
Mazurek S, Garroum I, Daraspe J, De Bellis D, Olsson V, Mucciolo A, Butenko MA, Humbel BM, Nawrath C. 2017. Connecting the molecular structure of cutin to ultrastructure and physical properties of the cuticle in petals of Arabidopsis. Plant Physiol, 173, 1146-1163.
https://dx.doi.org/10.1104/pp.16.01637
Meier AF, Suter M, Schraner EM, Humbel BM, Tobler K, Ackermann M, Laimbacher AS. 2017. Transfer of anti-rotavirus antibodies during pregnancy and in milk following maternal vaccination with an HSV-1 amplicon vector. Int J Mol Sci,18, 431-450.
http://www.mdpi.com/1422-0067/18/2/431
2016
Fabre G, Garroum I, Mazurek S, Daraspe J, Mucciolo A, Sankar M, Humbel B, Nawrath C. 2016. The ABCG transporter PEC1/ABCG32 is required for the formation of the developing leaf cuticle in Arabidopsis. New Phytol, 209, 192-201.
https://dx.doi.org/10.1111/nph.13608
Garroum I, Bidzinski P, Daraspe J, Mucciolo A, Humbel BM, Morel J-B, Nawrath C. 2016. Cuticular defects in Oryza sativa ATP-binding cassette transporter G31 mutant plants cause dwarfism, elevated defense responses and pathogen resistance Plant & Cell Physiology
https://doi.org/10.1093/pcp/pcw066
Barberon M, Vermeer JEM, De Bellis D, Wang P, Naseer S, Andersen TG, Humbel BM, Nawrath C, Takano J, Salt DE, Geldner N. 2016. Adaptation of Root Function by Nutrient-Induced Plasticity of Endodermal Differentiation. Cell, 164, 1-13.
http://dx.doi.org/10.1016/j.cell.2015.12.021
2015
Loussert Fonta C, Humbel BM. 2015. Correlative Microscopy. Arch Biochem Biophys, 581, 98-110.
https://dx.doi.org/10.1016/j.abb.2015.05.017
Kopp C, Domart-Coulon I, Escrig S, Humbel BM, Hignette M, Meibom A. 2015. Subcellular investigation of photosynthesis-driven carbon assimilation in the symbiotic reef coral Pocillopora damicornis. MBio, 6, 1-9.
http://mbio.asm.org/content/6/1/e02299-14
Kizilyaprak C, Daraspe J, Longo G, Humbel BM. 2015. Investigation of resins suitable for the preparation of biological sample for 3-D electron microscopy. J Struct Biol. 189, 135-146
http://dx.doi.org/10.1016/j.jsb.2014.10.009
Loussert Fonta C, Leis A, Mathisen C, Bouvier DS, Blanchard W, Volterra A, Lich B, Humbel BM. 2015. Analysis of acute brain slices by electron microscopy: A correlative light–electron microscopy workflow based on Tokuyasu cryo-sectioning. J Struct Biol, 189, 53-61
http://dx.doi.org/10.1016/j.jsb.2014.10.011
Takado Y, Knott G, Humbel BM, Escrig S, Mojgan M, Meibom A., Comment A. 2015. Imaging liver and brain glycogen metabolism at the nanometer scale. Nanomedicine: NBM. 11, 239-245
https://doi.org/10.1016/j.nano.2014.09.007
Takado Y, Knott G, Humbel BM, Masoodi M, Escrig S, Meibom A, Comment A. 2015. Imaging the time-integrated cerebral metabolic activity with subcellular resolution through nanometer-scale detection of biosynthetic products deriving from (13)C-glucose. J Chem Neuroanat, 69, 7-12.
https://doi.org/10.1016/j.jchemneu.2015.09.003
2014
Kizilyaprak C, Daraspe J, Humbel BM. 2014. Focused ion beam scanning electron microscopy in biology. Journal of Microscopy, 254, 109-114.
https://doi.org/10.1111/jmi.12127
Kizilyaprak C, Bittermann AG, Daraspe J, Humbel BM. 2014. FIB-SEM tomography in biology. Methods Mol Biol, 1117, 541-558.
http://link.springer.com/protocol/10.1007%2F978-1-62703-776-1_24
Schwarz H, Humbel BM. 2014. Correlative light and electron microscopy using immunolabeled resin sections. Methods Mol Biol, 1117, 559-592.
http://link.springer.com/protocol/10.1007%2F978-1-62703-776-1_25
2013
Oechslin F, Daraspe J, Giddey M, Moreillon P, Resch G. 2013. In vitro characterization of PlySK1249, a novel phage lysin, and assessment of its antibacterial activity in a mouse model of Streptococcus agalactiae bacteremia. Antimicrob Agents Chemother, 57, 6276-6283.
http://dx.doi.org/10.1128/AAC.01701-13
Broskey NT, Daraspe J, Humbel BM, Amati F. 2013. Skeletal muscle mitochondrial and lipid droplet content assessed with standardJized grid sizes for stereology, J Appl Physiol, 115, 765-770.
http://jap.physiology.org/content/115/5/765.long
Mazurek S, Mucciolo A, Humbel BM, Nawrath C. 2013. Transmission Fourier Transform Infrared Microspectroscopy allows the simultaneous assessment of cutin and cell wall polysaccharides of Arabidopsis petals. Plant J, 74, 880-891.
http://onlinelibrary.wiley.com/doi/10.1111/tpj.12164/
Humbel BM. 2013. Electron microscopy: Cryo-preparation in Roberts GCK (ed), Encyclopedia of Biophysics, Springer-Verlag, 596-600.
Humbel BM. 2013. Electron Microscopy: Classical Sample Preparation in Roberts GCK (ed), Encyclopedia of Biophysics, Springer-Verlag, 646-648.
2012
Karreman MA, Agronskaia AV, van Donselaar EG, Vocking K, Fereidouni F, Humbel BM, Verrips CT, Verkleij AJ, Gerritsen HC. 2012. Optimizing immuno-labeling for correlative fluorescence and electron microscopy on a single specimen. J Struct Biol, 180, 382-386.
https://doi.org/10.1016/j.jsb.2012.09.002
Loussert C, Forestier C-L, Humbel BM. 2012. Correlative Light and Electron Microscopy in Parasite Research. Mol Biol Cell, 111, 59-73.
https://doi.org/10.1016/B978-0-12-416026-2.00004-2
Van Opstal A, Bijvelt J, van Donselaar E, Humbel BM, Boonstra J. 2012. Inhibition of protein kinase B activity induces cell cycle arrest and apoptosis during early G1 phase in CHO cells. Cell Biol Int, 36, 357-365.
https://doi.org/10.1042/CBI20110092
Lamy CM, Sallin O, Loussert C, Chatton JY. 2012. Sodium sensing in neurons with a dendrimer-based nanoprobe. ACS Nano, 6, 1176–1187.
http://pubs.acs.org/doi/abs/10.1021/nn203822t
2011
Forestier C-L, Machu C, Loussert C, Pescher P, Späth GF. 2011. Imaging host cell-Leishmania interaction dynamics implicates parasite motility, lysosome recruitment, and host cell wounding in the infection process. Cell Host Microbe, 9, 319-330.
https://doi.org/10.1016/j.chom.2011.03.011
2010
Nadra K, Quignodon L, Sardella C, Joye E, Mucciolo A, Chrast R, Desvergne B. 2010. PPARγ in placental angiogenesis. Endocrinology, 151, 4969-4981.
https://doi.org/10.1210/en.2010-0131
Hayles MF, de Winter DAM, Schneijdenberg CTWM, Meeldijk JD, Luecken U, Persoon H, de Water J, de Jong F, Humbel BM, Verkleij AJ. 2010. The making of frozen-hydrated, vitreous lamellas from cells for cryo-electron microscopy. J Struct Biol, 172, 180-190.
https://doi.org/10.1016/j.jsb.2010.07.004
Van Laake LW, van Donselaar EG, Monshouwer-Kloots J, Schreurs C, Passier R, Humbel BM, Doevendans PA, Sonnenberg A, Verkleij AJ, Mummery CL. 2010. Extracellular matrix formation after transplantation of human embryonic stem cell-derived cardiomyocytes. Cell Mol Life Sci, 67, 277-290.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801836/?tool=pubmed
Fontaine T, Beauvais A, Loussert C, Thevenard B, Fulgsang CC, Ohno N, Clavaud C, Prevost MC, Latge J-P. 2010. Cell wall α-1-3-glucans induce the aggregation of germinating connidia of Aspergillus fumigatus. Fungal Genet Biol, 48, 707-712.
https://doi.org/10.1016/j.fgb.2010.04.006