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Rethinking the metabolism

Metabolomics, along with lipidomics, are powerful phenotyping technologies. They allow us to measure the polar and lipid metabolites with more specificity and sensitvity than ever before! Using metabolomic approaches, we are revealing the yet-unknown biological functions of well-known metabolites, getting new insights into metabolic signaling and pathway activity, discovering new metabolites and metabolic pathways…

In brief, with metabolomics, we are revisiting the metabolism & building upon the acquired knowledge of biochemistry!


david wishart

“There’s more to metabolites than metabolism; metabolites are perhaps the body’s most important signaling molecules”

David Wishart, University of Alberta, Edmonton, Canada, Physiological Reviews 2019
gary siuzdak

“Unlike genes or proteins, metabolites are readily available, typically inexpensive and their relatively simple structures make them amenable for bioactivity screening and clinical applications”

Gary Siuzdak, The Scripps Research Institute, CA, USA, Nature Biotechnology 2018
  • Lipids capture the essence of our chemical individuality
    Our latest work on Lausanne population is now online – the lipids that set us apart. Lipids reflect our chemical individuality far beyond the transcriptome, proteome and even polar metabolome! Within-subject variations, at timescale of ten years (!), are dwarfed by between-subject variations. Beyond high level of individuality, our circulatory lipid signatures are also sex-specific.…
  • Annual meeting of the Swiss Metabolomics Society
    This year, our annual meeting will take place at Inselspital in Bern on October 10th, featuring a compelling line-up of confirmed keynote speakers: For more information visit the SMS website
  • Welcome to Ioanna & Quentin!
    Ioanna Kyritsi and Quentin Brugnolo have joined us in February this year! We wish them a warm welcome! Ioanna holds a MsSc. in Biomedical Engineering (University of Grenoble Alpes, France) and is being trained in MS-based metabolomics along with lipidomics. Quentin has joined the team as a trainee, prior to starting his Bachelor in Life…