Table of contents
- Auditory cognition
- Visuomotor adaptation in real life and in virtual reality
- Brain reorganisation, effects of prism adaptation and virtual reality
In 2001 we were one of the first groups to demonstrate in human subjects that auditory information pertaining to the meaning and to the location of a sound is processed along two anatomically distinct streams, since then referred to as the What and Where streams. Several of our 68 original papers on this topic had deep impact on the field, as e. g. Rivier and Clarke 1997, with over 720 citations, and Maeder et al. 2001, with over 400 citations.
Visuomotor adaptation in real life and in virtual reality
Brain reorganisation, effects of prism adaptation and virtual reality
In a series of successful studies leading to seminal publications we showed how a therapeutic intervention targeting attention deficit changes the organization of the brain regions involved in attention processing in healthy subjects and in stroke patients and age-matched healthy subjects. The therapeutic intervention used in these studies, called prism adaptation (PA), is one of the main methods used to alleviate spatial attention deficits in stroke patients.
Our studies determined the mechanisms behind this intervention, and further provided biomarkers based on the location of the lesions, to determine patients who will be good responders to this intervention. An important, but surprisingly under-explored, field in this domain concerns the dynamic interaction between brain networks in stroke patients, and how this interaction is modulated by therapeutic interventions. In healthy subjects, we showed that the cognitive therapeutic intervention using prism adaptation changes the interplay between attentional networks. Attention deficits after stroke are known to be proportional to the disruption of the networks underlying attention, however, how therapeutic interventions change the interaction between these networks remains to be determined and is one of the main topic of our projects.