Cerebral plasticity following prismatic adaptation

Principal Investigator: Dr. Sonia Crottaz-Herbette

Overview

This project focuses on the plasticity following rehabilitation intervention on patients with right hemispheric damage. More specifically, we are using functional magnetic resonance imaging (fMRI) during cognitive tasks and resting state, as well as diffusion spectrum imaging (DSI) to investigate the effects of a promising rehabilitation method that can alleviate cognitive deficits of patients with brain damage. This method, called “prismatic adaptation” has recently received much attention as a potential method for the rehabilitation of unilateral neglect symptoms in patients with right hemispheric damage. Our goal is to characterize how specific brain networks are functionally and anatomically modified by prism adaptation, and more generally how healthy brains, left and right damaged brains react differently to a cognitive training.

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Collaborators

Dr. Sonia Crottaz-Herbette

Isabel Tissières, PhD student Lemanic Neuroscience doctoral school

Mona Elamly, Master student, Faculté de Biologie et Médecine, 2014-2016

Manon Durand-Ruel, EPFL Life sciences, Master student, trainee

Louis Gudmundsson, Doctoral MD student, Faculty of Biology and Medecine, Lausanne University

Alumni

Sujitha Kanagaratnam, Master student, Faculté de Biologie et Médecine, 2013-2015

Nicole Muller, Master student, Faculté de Biologie et Médecine, 2012-2014

Kathrin Ader, Master student, Faculté de Biologie et Médecine, 2011-2013

Funding

The work was supported by grants from the Swiss National Science Foundation to S. Crottaz-Herbette (Marie-Heim-Vögtlin fellowship FNS PMPDP3_129028) and S. Clarke (FNS 320030B-141177) and from the Biaggi Foundation to S. Crottaz-Herbette.