Very happy to share our latest review on probiotics in a diverse (microbial) world entitled “From global to local: rethinking the design of probiotic intervention strategies” in Trends in Microbiology that we wrote with Julian Garneau and Maria Gloria Dominguez Bello. In this review, we reflect on the need and utility of personalized probiotics, especially we discuss that:
– Personalized or regionally adapted probiotics may be more effective, especially when based on local strains and microbiome compositions.
– Personalization should be assessed based on a taxon’s adaptability—its capacity to undergo genomic or phenotypic changes that enable colonization of a given host or niche and finally that
– Personalized and local probiotics may not be cost-effective in market-driven systems; broader, holistic health strategies (including traditional knowledge and ecosystem preservation) may be more sustainable and equitable.
We also highlight and advocate for the need for more inclusive microbiome research on a global scale, expanding the initial framework by Ovokeraye Oduaran and colleagues put-forth in Nature Medicine in 2024: https://lnkd.in/eaQU-WhA by including aspects on microbial conservation, microbiota-targeted interventions and One Health.
Go read it!
https://lnkd.in/eEZXX4hz
From global to local: rethinking the design of probiotic intervention strategies
