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DBC News is a monthly publication that seeks to inform first and foremost faculty members, researchers and students. It also reaches out to a wider community - Department of Computational Biology partners, visiting faculty and friends.
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Alongside the Department's website it is a complementary means of keeping abreast of the Department's rich and diversified scientific activities - visiting faculty, exceptional conferences, publications, awards, appointments, calls for papers and research, ...
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The whole DBC extends the warmest of welcomes to new members.
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Prof. Dal Co is joining the DBC as a Tenure-track assistant professor. Learn more about the Dalcolab
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Doctoral Student, Group Malaspinas
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I am a graduate student with a Master in Biology from the University of Milan – Bicocca in Italy. During my studies, I started to get into the field of genomics and evolutionary biology showing a keen interest in computational approaches for biological research.
I have spent the last year of my Master at the Center for Evolutionary Hologenomics (University of Copenhagen – GLOBE institute) working on a research project that has become the subject of my master thesis. The focus of the project was the study of the animal microbiome in the context of a disease. Read more
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Post-doctoral student, Salamin Group
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Having recently defended my doctoral thesis in evolutionary biology under the supervision of Nicolas Lartillot at Université de Lyon, my work focused on modelling the interplay between mutation, selection and drift in the evolutionary processes of protein-coding DNA sequences. I am now continuing to pursue my research interests in Prof. Nicolas Salamin’s group as a postdoc, focusing on the long term evolution of phenotypic variance. Although my educational background is originally in biology, I enjoyed an interdisciplinary training at the crossroad between physics, computer science and mathematics.
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Dr. Adriaan van der Graaf
Post-doctoral student, Group Kutalik
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I'm a Dutch molecular biologist who has taken a keen interest in statistical approaches to biological data.
I followed a master program tailored to learning about statistics and inference from large biological data.
During my masters I ended up doing an internship at the Genetics department in Groningen, learning about how we can best predict polygenic scores for celiac disease.
Read more
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Bastien is joining Laurian as an IT and will be located in the same area as Laurian
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The DBC Seminars brings world leading computational scientists to present their work in a colloquium and to meet with faculty and students. The colloquium has broad attendance by faculty, staff, masters and PhD students from the University and EPFL
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September 16th - DBC Seminar with
Dr. Maria Carolina Borges, Vice Chancellor's Research Fellow at the MRC Integrative Epidemiology Unit, University of Bristol
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"Integrating genetics and causal inference to understand complex diseases in human populations"
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When : Septemner 16th - at 12h30
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Where : Génopode - Auditoire A
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If you want to join online - Zoom
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Summary of presentation: In this talk, I will discuss my work focusing on using Mendelian randomization in large-scale population studies to unravel the role of metabolites, particularly fatty acids, in the aetiology of cardiovascular diseases and to improve the evidence basis on the impact of maternal adiposity on pregnancy-related disorders.
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September 23rd - DBC Seminar with with Prof. Raphael Gottardo - Futur Director of the Medical Bioinformatic Center of CHUV
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"Analyzing spatial gene expression architecture in tissue sections at increased resolution"
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When : Septemner 23rd - at 12h15
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Where : Génopode - Auditoire A
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If you want to join online - Zoom
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Abstract : Recent spatial gene expression technologies have enabled comprehensive
measurement of transcriptomic profiles while retaining spatial context. However, existing analysis methods do not address the limited resolution of the technology or use the spatial information efficiently. During this talk, I will present BayesSpace, a fully
Bayesian statistical method that uses the information from spatial neighborhoods for resolution enhancement of spatial transcriptomic data and for clustering analysis. I will show how BayesSpace can be used to improve the identification of distinct intra-tissue
transcriptional profiles from samples of the brain, melanoma, invasive ductal carcinoma and ovarian adenocarcinoma. Using immunohistochemistry and an in silico dataset constructed from scRNA-seq data, I will then show that BayesSpace resolves tissue structure
that is not detectable at the original resolution and identifies transcriptional heterogeneity inaccessible to histological analysis.
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Bioinformatics : Using big data to advance medical therapies by Marie Sadler
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Completed project: efficient analysis of genomic data
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Prof. Salamin and Dessimoz, in collaboration with other Principal investigators from UNIL and UNIGE explain what the "efficient analysis of genomic data" project is.
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20 fully funded PhD fellowships in Quantitative Biology
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2021 Postdoc Retreat Sept. 11th – 12th
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Join the APNS at the Chalet, Le Vaticamp and meet former postdocs that moved on to many different careers including academia, industry, scientific publishing, consulting, start-ups, clinical settings, etc. Hear about their very personal career paths, ask all the questions that are on your mind about your next career steps, exchange with fellow postdocs, expand your … Read more
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JOIN THE COMPUTATIONAL DISCUSSION
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July 7th - 17:30-19h30, on Zoom
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The [BC]2 Basel Computational Biology Conference provides a unique platform to scientists at all career stages to present their research. It unites researchers from academia, industry and healthcare working in a broad range of disciplines: from deciphering spatiotemporal gene expression patterns, to modelling evolutionary dynamics or acquiring a better understanding of how genetics influence human health. Read More
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Horizon Europe 2021-2022 Work Programmes are out!
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The European Commission has published the Work Programmes of Horizon Europe for the 2021-2022 period, with a total budget of €14.7 billion. Researchers and innovators in Switzerland can participate in most collaborative projects and their funding is secure
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VIP2 Post Doc Fellows
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VIP2 is a postdoctoral fellowship program at the Vienna BioCenter (VBC) offering three – year fellowships that are open to candidates with backgrounds in biology, chemistry, physics, medicine, engineering, computer science, and bioinformatics.
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What follows is a small sampling of recently published research across the department — for a more complete list of publications, visit PubMed. If there is a paper you would like to see highlighted in the next issue of the newsletter, please email us.
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Are you an alum or former employee of the department? Email us our news and updates to include in an upcoming newsletter!
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Our new Twitter Feed
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We have just released our new Twitter page.
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Make sure to follow the DBC.
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