{"id":1759,"date":"2024-01-09T10:16:37","date_gmt":"2024-01-09T09:16:37","guid":{"rendered":"https:\/\/wp.unil.ch\/sgg\/?page_id=1759"},"modified":"2024-12-06T12:08:15","modified_gmt":"2024-12-06T11:08:15","slug":"2024-2","status":"publish","type":"page","link":"https:\/\/wp.unil.ch\/sgg\/2024-2\/","title":{"rendered":"2024"},"content":{"rendered":"\n<p>[12] <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39635766\/\">Lipid disturbances induced by psychotropic drugs: clinical and genetic predictors for early worsening of lipid levels and new-onset dyslipidaemia in Swiss psychiatric samples.<\/a> Delacr\u00e9taz A, <strong>Sadler M<\/strong>, Gamma F, Preisig M, Richard-Lepouriel H, von Gunten A, Conus P, Plessen KJ, <strong>Kutalik Z<\/strong>, Eap CB. <strong><em>BJPsych Open<\/em><\/strong>. 2024 Dec 5;10(6):e227.\u00a0<\/p>\n\n\n\n<p>[11] <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39632930\/\">Identification of rare disease genes as drivers of common diseases through tissue-specific gene regulatory networks.<\/a> Bakker OB, Claringbould A, Westra HJ, Wiersma H, Boulogne F, V\u00f5sa U, Urz\u00faa-Traslavi\u00f1a CG, Mulcahy Symmons S, Zidan MMM, <strong>Sadler MC, Kutalik Z<\/strong>, Jonkers IH, Franke L, Deelen P. <strong><em>Sci Rep.<\/em><\/strong> 2024 Dec 4;14(1):30206.<\/p>\n\n\n\n<p>[10] <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39548087\/\">Psychotropic-induced weight gain and telomere length: results from a one-year longitudinal study and a large population-based cohort.<\/a> Piras M, Lin J, <strong>Sadler MC<\/strong>, Ranjbar S, Grosu C, Laaboub N, Preisig M, Gamma F, Plessen KJ, von Gunten A, Conus P,<strong> Kutalik Z<\/strong>, Eap CB. <strong><em>Transl Psychiatry<\/em><\/strong>. 2024 Nov 15;14(1):471.\u00a0<\/p>\n\n\n\n<p>[9] <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39152035\/\">Widespread natural selection on metabolite levels in humans.<\/a> <strong>Timasheva Y, Lepik K<\/strong>, Liska O, Papp B, <strong>Kutalik Z<\/strong> <strong><em>Genome Res<\/em><\/strong>. 2024 Sep 9. doi: 10.1101\/gr.278756.123.&nbsp;<\/p>\n\n\n\n<p>[8] <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39332408\/\">Disentangling mechanisms behind the pleiotropic effects of proximal 16p11.2 BP4-5 CNVs.<\/a> <strong>Auwerx C, Moix S, Kutalik Z<\/strong>*, Reymond A* <strong><em>Am J Hum Genet<\/em><\/strong>. 2024 Sep 23:S0002-9297(24)00300-8.<\/p>\n\n\n\n<p>[7] <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39332410\/\">The pleiotropic spectrum of proximal 16p11.2 CNVs.<\/a> <strong>Auwerx C, Kutalik Z<\/strong>*, Reymond A* <strong><em>Am J Hum Genet<\/em><\/strong>. 2024 Sep 23:S0002-9297(24)00301-X.<\/p>\n\n\n\n<p>[6] <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38760657\/\">Breaking down causes, consequences, and mediating effects of telomere length variation on human health.<\/a> <strong>Moix S, Sadler MC, Kutalik Z*, Auwerx C*<em> Genome Biol<\/em><\/strong>. 2024 May 17;25(1):125.<\/p>\n\n\n\n<p>[5] <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38689001\/\" data-type=\"link\" data-id=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38689001\/\">Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.<\/a> Keaton JM <em>et al<\/em> <strong><em>Nat Genet<\/em><\/strong>. 2024 May;56(5):778-791.<\/p>\n\n\n\n<p>[4] <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38419113\/\">DNA methylation may partly explain psychotropic drug-induced metabolic side effects: results from a prospective 1-month observational study.<\/a> Dubath C, <strong>Porcu E<\/strong>, Delacr\u00e9taz A, Grosu C, Laaboub N, Piras M, von Gunten A, Conus P, Plessen KJ, <strong>Kutalik Z<\/strong>, Eap CB. <strong><em>Clin Epigenetics<\/em><\/strong>. 2024 Feb 28;16(1):36<\/p>\n\n\n\n<p>[3] <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38360877\/\">PheWAS-based clustering of Mendelian Randomisation instruments reveals distinct mechanism-specific causal effects between obesity and educational attainment.<\/a> <strong>Darrous L<\/strong>, Hemani G, Davey Smith G, <strong>Kutalik Z.<\/strong> <strong><em>Nat Commun<\/em><\/strong>. 2024 Feb 15;15(1):1420.&nbsp;<\/p>\n\n\n\n<p>[2] <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38243142\/\">Causality-enriched epigenetic age uncouples damage and adaptation.<\/a> Ying K, Liu H, Tarkhov AE, <strong>Sadler MC<\/strong>, Lu AT, Moqri M, Horvath S, <strong>Kutalik Z<\/strong>, Shen X, Gladyshev VN. <strong><em>Nat Aging<\/em><\/strong>. 2024 Jan 19. doi: 10.1038\/s43587-023-00557-0.<\/p>\n\n\n\n<p>[1] <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38185688\/\">Rare copy-number variants as modulators of common disease susceptibility.<\/a> <strong>Auwerx C<\/strong>, J\u00f5eloo M, <strong>Sadler MC<\/strong>, Tesio N, <strong>Ojavee S<\/strong>, Clark CJ, M\u00e4gi R; Estonian Biobank Research Team; Reymond A*, <strong>Kutalik Z<\/strong>* <strong><em>Genome Med<\/em><\/strong>. 2024 Jan 8;16(1):5. doi: 10.1186\/s13073-023-01265-5.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>[12] Lipid disturbances induced by psychotropic drugs: clinical and genetic predictors for early worsening of lipid levels and new-onset dyslipidaemia in Swiss psychiatric samples. 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