{"id":1469,"date":"2021-02-01T18:00:26","date_gmt":"2021-02-01T17:00:26","guid":{"rendered":"https:\/\/wp.unil.ch\/sgg\/?page_id=1469"},"modified":"2021-12-16T09:12:24","modified_gmt":"2021-12-16T08:12:24","slug":"2021-2","status":"publish","type":"page","link":"https:\/\/wp.unil.ch\/sgg\/2021-2\/","title":{"rendered":"2021"},"content":{"rendered":"

[17] Simultaneous estimation of bi-directional causal effects and heritable confounding from GWAS summary statistics.<\/a> Darrous L*, Mounier N*, Kutalik Z. <\/span><\/strong>Nat Commun<\/strong><\/em>. 2021 Dec 14;12(1):7274.\u00a0<\/span><\/p>\n

[16] The power of genetic diversity in genome-wide association studies of lipids.<\/a> Graham SE et al. <\/span>Nature<\/strong><\/em>. 2021 Dec 9. doi: 10.1038\/s41586-021-04064-3.<\/span><\/p>\n

[15] Probabilistic inference of the genetic architecture underlying functional enrichment of complex traits. <\/strong><\/a>Patxot M,<\/strong> Banos DT, Kousathanas A, Orliac EJ, Ojavee SE<\/strong>, Moser G, Holloway A, Sidorenko J, Kutalik Z<\/strong>, M\u00e4gi R, Visscher PM, R\u00f6nneg\u00e5rd L, Robinson MR. <\/span>Nat Commun<\/strong><\/em>. 2021 Nov 30;12(1):6972.<\/span><\/p>\n

[14] Untargeted Metabolome- and Transcriptome-Wide Association Study Suggests Causal Genes Modulating Metabolite Concentrations in Urine.<\/a>\u00a0S\u00f6nmez Flitman R, Khalili B, Kutalik Z<\/strong>, Rueedi R, Br\u00fcmmer A, Bergmann S. <\/span>J Proteome Res<\/strong><\/em>. 2021 Oct 26. doi: 10.1021\/acs.jproteome.1c00585.<\/span><\/p>\n

[13] Mendelian randomization to assess causality between uromodulin, blood pressure and chronic kidney disease.<\/a>\u00a0Ponte B*, Sadler MC*<\/strong>, Olinger E, Vollenweider P, Bochud M, Padmanabhan S, Hayward C*, Kutalik Z*<\/strong>, Devuyst O*. <\/span>Kidney Int<\/strong><\/em>. 2021 Oct 9:S0085-2538(21)00922-4.<\/span><\/p>\n

[12] Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome.<\/a> Porcu E, Sadler MC, Lepik K, Auwerx C,<\/strong> Wood AR, Weihs A, Sleiman MSB, Ribeiro DM, Bandinelli S, Tanaka T, Nauck M, V\u00f6lker U, Delaneau O, Metspalu A, Teumer A, Frayling T, Santoni FA, Reymond A*, Kutalik Z* <\/strong><\/span>Nat Commun<\/strong><\/em>. 2021 Sep 24;12(1):5647.<\/span><\/p>\n

[11] Composite trait Mendelian randomization reveals distinct metabolic and lifestyle consequences of differences in body shape. <\/a>Sulc J, Sonrel A, Mounier N, Auwerx C<\/strong>, Marouli E, Darrous L<\/strong>, Draganski B, Kilpel\u00e4inen TO, Joshi P, Loos RJF, Kutalik Z. Nat<\/em>\u00a0<\/strong><\/span>Commun Biol<\/strong><\/em>. 2021 Sep 13;4(1):1064.<\/span><\/p>\n

[10] Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression. <\/a>V\u00f5sa U et al. <\/em><\/span>Nat Genet<\/strong><\/em>. 2021 Sep;53(9):1300-1310.<\/span><\/p>\n

[9] Genetic insights into biological mechanisms governing human ovarian ageing. <\/a>Ruth KS et al. <\/span>Nature.<\/strong> <\/em>2021 Aug 4. doi: 10.1038\/s41586-021-03779-7.<\/span><\/p>\n

[8] HSD17B7 gene in self-renewal and oncogenicity of keratinocytes from Black versus White populations. <\/a>Xu X, Tassone B, Ostano P, Katarkar A, Proust T, Joseph JM, Riganti C, Chiorino G, Kutalik Z<\/strong>, Lefort K, Dotto GP. <\/span>EMBO Mol Med.<\/strong><\/em> 2021 Jul 7;13(7):e14133.<\/span><\/p>\n

[7] Socio-economic position as a moderator of cardiometabolic outcomes in patients receiving psychotropic treatment associated with weight gain: results from a prospective 12-month inception cohort study and a large population-based cohort. <\/a>Dubath C, Gholam-Rezaee M, Sjaarda J<\/strong>, Levier A, Saigi-Morgui N, Delacr\u00e9taz A, Glatard A, Panczak R, Correll CU, Solida A, Plessen KJ, von Gunten A, Kutalik Z<\/strong>, Conus P, Eap CB. <\/span>Transl Psychiatry<\/strong><\/em>. 2021 Jun 26;11(1):360.\u00a0<\/span><\/p>\n

[6] The trans-ancestral genomic architecture of glycemic traits.<\/a> Chen J et al.<\/em> <\/span>Nat Genet.<\/strong><\/em> 2021 Jun;53(6):840-860.<\/span><\/p>\n

[5] Genomic architecture and prediction of censored time-to-event phenotypes with a Bayesian genome-wide analysis.<\/a> Ojavee SE<\/strong>, Kousathanas A, Trejo Banos D, Orliac EJ, Patxot M<\/strong>, L\u00e4ll K, M\u00e4gi R, Fischer K, Kutalik Z<\/strong>, Robinson MR. <\/span>Nat Commun<\/strong><\/em>. 2021 Apr 20;12(1):2337.\u00a0<\/span><\/p>\n

[4] Triangulating evidence from longitudinal and Mendelian randomization studies of metabolomic biomarkers for type 2 diabetes.<\/a> Porcu E<\/strong>, Gilardi F, Darrous L<\/strong>, Yengo L, Bararpour N, Gasser M, Marques-Vidal P, Froguel P, Waeber G, Thomas A, Kutalik Z<\/strong>. <\/span>Sci Rep<\/strong><\/em>. 2021 Mar 18;11(1):6197.<\/span><\/p>\n

[3] Gene regulation contributes to explain the impact of early life socioeconomic disadvantage on adult inflammatory levels in two cohort studies.<\/a> Carmeli C, Kutalik Z,<\/strong> Mishra PP, Porcu E<\/strong>, Delpierre C, Delaneau O, Kelly-Irving M, Bochud M, Dhayat NA, Ponte B, Pruijm M, Ehret G, K\u00e4h\u00f6nen M, Lehtim\u00e4ki T, Raitakari OT, Vineis P, Kivim\u00e4ki M, Chadeau-Hyam M, Dermitzakis E, Vuilleumier N, Stringhini S. <\/span>Sci Rep<\/strong><\/em>. 2021 Feb 4;11(1):3100.<\/span><\/p>\n

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[2] Obesity and atypical depression symptoms: findings from Mendelian randomization in two European cohorts. <\/a>Pistis G, Milaneschi Y, Vandeleur CL, Lasserre AM, Penninx BWJH, Lamers F, Boomsma DI, Hottenga JJ, Marques-Vidal P, Vollenweider P, Waeber G, Aubry JM, Preisig M, Kutalik Z<\/strong>. <\/span>Transl Psychiatry<\/strong><\/em>. 2021 Feb 4;11(1):96.<\/span><\/p>\n<\/div>\n<\/div>\n

[1] Genome-Wide Association Study of Circulating Interleukin 6 Levels Identifies Novel Loci.<\/a> Ahluwalia TS et al. <\/span>Hum Mol Genet<\/strong><\/em>. 2021 Jan 30:ddab023. doi: 10.1093\/hmg\/ddab023. Online ahead of prin<\/span><\/p>\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

[17] Simultaneous estimation of bi-directional causal effects and heritable confounding from GWAS summary statistics. Darrous L*, Mounier N*, Kutalik Z. Nat Commun. 2021 Dec 14;12(1):7274.\u00a0 [16] The power of genetic … <\/p>\n","protected":false},"author":970,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","footnotes":""},"class_list":["post-1469","page","type-page","status-publish"],"_links":{"self":[{"href":"https:\/\/wp.unil.ch\/sgg\/wp-json\/wp\/v2\/pages\/1469","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wp.unil.ch\/sgg\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/wp.unil.ch\/sgg\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/wp.unil.ch\/sgg\/wp-json\/wp\/v2\/users\/970"}],"replies":[{"embeddable":true,"href":"https:\/\/wp.unil.ch\/sgg\/wp-json\/wp\/v2\/comments?post=1469"}],"version-history":[{"count":0,"href":"https:\/\/wp.unil.ch\/sgg\/wp-json\/wp\/v2\/pages\/1469\/revisions"}],"wp:attachment":[{"href":"https:\/\/wp.unil.ch\/sgg\/wp-json\/wp\/v2\/media?parent=1469"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}