Cell culture facility
The Stem Cell & Organoid Facility (SCOF) is the ultimate destination for advanced cell culture, excelling particularly in organoids and stem cells. Imagine a cutting-edge lab equipped with 8 high-performance PHCBI incubators and 5 top-tier HERASAFE 230i hoods, all designed to provide unparalleled cell culture conditions. Inside the hoods, we have two microscopes that enable precise manipulation of iPSCs, removal of differentiated parts, clone picking, and other meticulous tasks required for iPSC work. These state-of-the-art resources create a premier environment for pioneering research in stem cells and organoids, propelling groundbreaking discoveries in biomedical science.
ImageXpress Confocal HT.ai system
Step into the future with the ImageXpress Confocal HT.ai System. With a multi-laser light sources, a deep tissue-penetrating confocal disk module, water immersion objectives, and cutting-edge machine learning analysis software. This advanced setup is perfect for tackling highly complex cell-based and 3D assays. The seven-channel high-intensity lasers illuminate samples with extraordinary brightness and superior signal-to-background ratios. The spinning confocal disk technology allows for deeper tissue penetration, producing sharper, higher-resolution images. Water immersion objectives amplify the signal fourfold at lower exposure times, enhancing sensitivity and image clarity without sacrificing speed. For advanced analysis, the optional IN Carta software employs intuitive, modern machine learning, turning intricate data into insightful discoveries. This system revolutionizes cell imaging and analysis, making it indispensable for groundbreaking research.
ECHO Revolve
Revolve is the world’s first and only hybrid microscope, combining four microscopes into one, significantly reducing equipment costs and freeing up valuable laboratory space. It features an upright configuration ideal for glass slides and an inverted setup for live samples in dishes, wells, and flasks. The transmitted light mode includes Brightfield, Darkfield, Phase Contrast, and Polarized Light, while the fluorescence mode offers automated LED illumination with one-touch image overlay. This innovative design allows lab members to configure the microscope to suit their specific needs, eliminating the need to choose between different systems.
Merscope Spatial Transcriptomics
Discover the groundbreaking capabilities of MERSCOPE, utilizing revolutionary MERFISH technology to map and quantify the spatial distribution of RNA species in individual cells with unparalleled precision, all without the need for downstream sequencing. This advanced instrument comprises an imaging box and a processing computer, delivering exceptional sensitivity for detecting low-expressing genes and achieving sub-cellular resolution with ≤100 nm accuracy.
MERSCOPE’s robust multiplexing can handle up to 1000 genes, making it an incredibly versatile tool for analyzing specified genes across a wide variety of samples and tissues. The system’s intuitive automation and comprehensive reagent packs ensure ease of use, while its sophisticated combinatorial labeling, sequential imaging, and error-robust barcoding guarantee the highest levels of detection efficiency and resolution in spatial transcriptome profiling. From whole tissue sections to single-cell and sub-cellular imaging, MERSCOPE sets a new standard in spatial genomics.
CelVivo Stress Free – 3D
CelVivo is pushing the frontiers of in vitro models by innovating 3D cell culture research, eliminating active diffusion bias and shear stress. This enables cells to exhibit physiological performance and intercellular communication akin to in vivo conditions, whether they are spheroids, organoids, or other aggregates. The ClinoStar 3D cell culture technology supports the cultivation and maturation of cells across various applications, generating uniform, reproducible, and functional spheroids that mimic in vivo cell function, structure, and architecture. This technology bridges the gap between 2D cell culture and cell function, enhancing research relevance.
Invitrogen Neon NxT Electroporation System
The Invitrogen Neon NxT Electroporation System is designed to protect your valuable research time and samples with performance, speed, simplicity, and flexibility. It utilizes proprietary pipette tip technology and a simplified workflow to minimize sample loss and contamination risk while enhancing experimental control. The system provides proven transfection efficiency and cell viability, even for challenging cell lines, and allows precise optimization of electroporation parameters for various cell types and protocols. It also enhances genome editing efficiency with optimized CRISPR delivery buffers and features a quick three-step workflow with an intuitive interface, preserving precious samples and reducing contamination risks.
Chromium iX
The Chromium X Series is designed to meet your single cell analysis needs at any stage, offering unmatched flexibility and scalability. Start with the Chromium iX for cost-effective, lower throughput single cell analysis, with the option to upgrade to the full-range, high-throughput Chromium X. This series accommodates any 10x Genomics single cell assay, providing the industry’s highest throughput flexibility, allowing you to analyze from hundreds to hundreds of thousands of cells per run. For large-scale studies, the Chromium X makes high-throughput single cell gene expression and immune profiling more affordable and practical. With convenient 10x Genomics Cloud connectivity, you can easily manage your instrument, receive software updates, and monitor usage wirelessly. Plus, the Chromium iX is future-proof, offering an easy upgrade to the Chromium X with just a software update, ensuring your system evolves as your research demands grow.
