MER
Faculté SB – EPFL
Département ou laboratoire: ISIC [site web]
georges.wagnieres@epfl.ch
Tél. +41 21 693 31 20
Langues d’enseignement
Français, Anglais
Thèmes de prédilection
Optical detection of cancers
Optical therapeutic methods
Mechanistic studies of phototherapies
Fundamental studies of the tissue optical properties
Compétences élargies
Biomedical Optics
Photomedicine
Thèmes de recherche spécifique
– Detection of early cancers by fluorescence imaging and spectroscopy.
– Characterization of superficial cancers by high magnification endoscopy.
– Clinical study of the tissue spectrofluorometry (steady-state and time-resolved) applied to: the study of the pharmacokinetics of photosensitizers, and the spectral design of clinical cancer photodetection apparatus.
– Preclinical and clinical evaluation of photosensitizers for photodynamic therapy of cancers, Crohn’s disease, ulcerative colitis, acne and age-related conditions, including age-related macular degeneration.
– Preclinical study of actives inducing a modulation of the angiogenesis associated with diseases like cancer, exudative age related macular degeneration and rheumatoid arthritis.
– In vivo measurement of the vascular and tissular oxygen concentration using phosphorescing and delayed fluorescence quenching.
– Study of the light dosimetry, light delivery and tissue optical spectroscopy.
– Study of the laser-tissue interactions in ophthalmology.