{"id":6,"date":"2019-11-28T16:00:19","date_gmt":"2019-11-28T15:00:19","guid":{"rendered":"http:\/\/wp.unil.ch\/modele\/?page_id=6"},"modified":"2025-11-27T11:45:53","modified_gmt":"2025-11-27T10:45:53","slug":"home","status":"publish","type":"page","link":"https:\/\/wp.unil.ch\/metabolomics\/","title":{"rendered":"Rethinking the metabolism"},"content":{"rendered":"\n

Metabolomics<\/strong>, along with lipidomics<\/strong>, is a powerful phenotyping technology. It allows us to measure polar and lipid metabolites with greater specificity and sensitvity than ever before! Using metabolomic approaches, we are uncovering previously unknown biological functions of well-known metabolites, getting new insights into metabolic signaling and pathway activity, and discovering new metabolites and metabolic pathways…<\/p>\n\n\n\n

In brief, with metabolomics, we are revisiting the metabolism & building upon the acquired knowledge of biochemistry!<\/p>\n\n\n\n

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“There\u2019s more to metabolites than metabolism; metabolites are perhaps the body\u2019s most important signaling molecules”<\/em><\/p>\n\u2014 David Wishart, University of Alberta, Edmonton, Canada, Physiological Reviews 2019<\/a><\/em><\/cite><\/blockquote>\n\n\n

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“Unlike genes or proteins, metabolites are readily available, typically inexpensive and their relatively simple structures make them amenable for bioactivity screening and clinical applications”<\/em><\/p>\n\u2014 Gary Siuzdak, The Scripps Research Institute, CA, USA<\/em>, Nature Biotechnology 2018<\/a><\/em><\/cite><\/blockquote>\n\n\n