{"id":421,"date":"2023-02-08T10:46:00","date_gmt":"2023-02-08T09:46:00","guid":{"rendered":"https:\/\/wp.unil.ch\/langletlab\/?page_id=421"},"modified":"2025-11-08T14:09:36","modified_gmt":"2025-11-08T13:09:36","slug":"project-1","status":"publish","type":"page","link":"https:\/\/wp.unil.ch\/langletlab\/project-1\/","title":{"rendered":"Project 1"},"content":{"rendered":"\n<h2 class=\"wp-block-heading has-accent-color has-text-color has-link-color wp-elements-e1ff413c0380c2e7243f1b29055235f5\" style=\"font-size:40px\">Heterogeneity among tanycyte populations and tanycyte\/neuron partnerships<\/h2>\n\n\n\n<p style=\"font-size:24px;font-style:normal;font-weight:200;letter-spacing:1px\">The arcuate nucleus of the hypothalamus (ARH) and the median eminence (ME) are key regions for integrating metabolic information and regulating energy balance. These regions contain multiple interacting cell types\u2014including NPY and POMC neurons, tanycytes, astrocytes, oligodendrocytes, and endothelial cells\u2014that sense and respond to metabolic changes. Tanycytes, lining the floor of the third ventricle and extending a single basal process into the hypothalamic parenchyma, contact blood vessels, glial cells, and neurons. Yet, the heterogeneity of tanycytes and the dynamics of their cellular contacts under different metabolic states remain largely unknown.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p style=\"font-size:24px;font-style:normal;font-weight:200\"><strong>Our projects include:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li style=\"font-size:24px;font-style:normal;font-weight:200\">Dissecting tanycyte morphology and ultrastructure<\/li>\n\n\n\n<li style=\"font-size:24px;font-style:normal;font-weight:200\">Deciphering gene expression patterns along the third ventricle<\/li>\n\n\n\n<li style=\"font-size:24px;font-style:normal;font-weight:200\">Defining plasticity according to metabolic state<\/li>\n\n\n\n<li style=\"font-size:24px;font-style:normal;font-weight:200\">Inferring cell\u2013cell communication within the hypothalamic network<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Heterogeneity among tanycyte populations and tanycyte\/neuron partnerships The arcuate nucleus of the hypothalamus (ARH) and the median eminence (ME) are key regions for integrating metabolic information and regulating&hellip;<\/p>\n","protected":false},"author":1002480,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-full-width.php","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","footnotes":""},"class_list":["post-421","page","type-page","status-publish","has-post-thumbnail"],"_links":{"self":[{"href":"https:\/\/wp.unil.ch\/langletlab\/wp-json\/wp\/v2\/pages\/421","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wp.unil.ch\/langletlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/wp.unil.ch\/langletlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/wp.unil.ch\/langletlab\/wp-json\/wp\/v2\/users\/1002480"}],"replies":[{"embeddable":true,"href":"https:\/\/wp.unil.ch\/langletlab\/wp-json\/wp\/v2\/comments?post=421"}],"version-history":[{"count":4,"href":"https:\/\/wp.unil.ch\/langletlab\/wp-json\/wp\/v2\/pages\/421\/revisions"}],"predecessor-version":[{"id":689,"href":"https:\/\/wp.unil.ch\/langletlab\/wp-json\/wp\/v2\/pages\/421\/revisions\/689"}],"wp:attachment":[{"href":"https:\/\/wp.unil.ch\/langletlab\/wp-json\/wp\/v2\/media?parent=421"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}