{"id":195,"date":"2020-11-11T09:32:00","date_gmt":"2020-11-11T08:32:00","guid":{"rendered":"http:\/\/wp.unil.ch\/knobloch-lab\/?page_id=195"},"modified":"2026-02-23T14:55:50","modified_gmt":"2026-02-23T13:55:50","slug":"publications","status":"publish","type":"page","link":"https:\/\/wp.unil.ch\/knobloch-lab\/home\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"\n

A complete list of publications can be found in Pubmed<\/strong><\/a> or on the University server IRIS<\/strong><\/a>. Here are the latest published articles displayed.<\/p>\n\n\n\n

Nature Cell Biology, 2026<\/h2>\n\n\n\n

Cellular mechanisms of brain lipid metabolism in health and disease<\/a>https:\/\/www.nature.com\/articles\/s41556-026-01880-5<\/a><\/p>\n\n\n\n

Petrelli F., Gilardi C., Igelbu\u0308scher C.M., Panfilova D., Rey A., Paolicelli R.C., & Knobloch M. Nat Cell Biol<\/em> (2026). https:\/\/doi.org\/10.1038\/s41556-026-01880-5s41467-024-49449-w<\/p>\n\n\n\n

BioRxiv, 2026<\/h2>\n\n\n\n

Distinct epigenetic and metabolic states reflect the regional identity of adult neural stem cells and prime their fate<\/a><\/p>\n\n\n\n

Scandella V., Lykoskoufis N., Soldati H., Di Martino L., Teav T., Gallart-Ayala H., Ivanisevic J., Braun S.M.G#, Knobloch M#. BioRxiv Jan 2026, doi: https:\/\/doi.org\/10.1101\/2024.06.12.598519<\/p>\n\n\n\n

#last shared<\/p>\n\n\n\n

Nature Communications, 2024<\/h2>\n\n\n\n

A fluorescent perilipin 2 knock-in mouse model reveals a high abundance of lipid droplets in the developing and adult brain<\/a><\/p>\n\n\n\n

Madsen S., Delgado A.C., Cadilhac C., Maillard V., Battiston F., Igelbuescher C.M., De Neck S., Magrinelli E., Jabaudon D., Telley L., Doetsch F., Knobloch M. Nat Commun<\/em> 15<\/strong>, 5489 (2024). https:\/\/doi.org\/10.1038\/s41467-024-49449-w<\/p>\n\n\n\n

BioRxiv, 2024<\/h2>\n\n\n\n

An optimized method to visualize lipid droplets in brain tissue demonstrates their substantial accumulation in aged brains<\/a><\/p>\n\n\n\n

Petrelli F.*, Rey A.*, Panfilova D., Madsen S., H\u00e9ritier N., Knobloch M. BioRxiv June 13 2024, doi: https:\/\/doi.org\/10.1101\/2024.06.12.598519<\/p>\n\n\n\n

*first shared<\/p>\n\n\n\n

Trends in Endocrinology and Metabolism, 2023<\/h2>\n\n\n\n

Neural stem cell metabolism revisited: a critical role for mitochondria<\/a><\/p>\n\n\n\n

Scandella V*, Petrelli F*, Moore D.L., Braun S.M.G and Knobloch M.<\/p>\n\n\n\n

*first shared<\/p>\n\n\n\n

Science Advances, 2023<\/h2>\n\n\n\n

Mitochondrial pyruvate metabolism regulates the activation of quiescent neural stem cells<\/a><\/p>\n\n\n\n

Petrelli F*., Scandella V*, Montesuit S., Zamboni N., Martinou J.C.#, Knobloch M.#, Science Advances, 9; eadd522, 2023 March 1. <\/p>\n\n\n\n

*first shared, #last shared<\/p>\n\n\n\n

BioRxiv, 2022<\/h2>\n\n\n\n

A fluorescent perilipin 2 knock-in mouse model visualizes lipid droplets in the developing and adult brain<\/a><\/p>\n\n\n\n

Madsen S., Delgado A.C., Cadilhac C., Battiston F., Maillard V., Magrinelli E., Jabaudon D., Telley L., Doetsch F., Knobloch M.#, BioRxiv 2022 June 20. <\/p>\n\n\n\n

BioRxiv, 2022<\/h2>\n\n\n\n

Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells<\/a><\/p>\n\n\n\n

Petrelli F*., Scandella V*, Montesuit S., Zamboni N., Martinou J.C.#, Knobloch M.#, BioRxiv 2022 May 31. <\/p>\n\n\n\n

*first shared, #last shared<\/p>\n\n\n\n

Current Opinion in Lipidology, 2022<\/strong><\/strong><\/h2>\n\n\n\n

Brain lipid metabolism: the emerging role of lipid droplets in glial cells. <\/a>Petrelli F., Knobloch M., Amati F. Curr Opin Lipidol. 2022 Feb 1;33(1):86-87.<\/p>\n\n\n\n

Nature Communications, 2021<\/strong><\/strong><\/strong><\/h2>\n\n\n\n

Lipid droplet availability affects neural stem\/progenitor cell metabolism and proliferation<\/a>. <\/a>Ramosaj M*., Madsen S*., Maillard V., Scandella V., Sudria-Lopez D., Yuizumi N., Telley L., Knobloch M. 2021, Nat. Commun 12; 7362. <\/p>\n\n\n\n

*first shared<\/p>\n\n\n\n

Immunometabolism, 2021<\/strong><\/strong><\/strong><\/h2>\n\n\n\n

Myeloid Metabolism as a New Target for Rejuvenation?\u2014Comments on Restoring Metabolism of Myeloid Cells Reverses Cognitive Decline in Ageing (Nature. 2021 Feb;590(7844):122-128). <\/a>Knobloch M and Paolicelli R.C., Immunometabolism, 2021;3(4):e210034.<\/p>\n\n\n\n

Development, 2021<\/strong><\/h2>\n\n\n\n

Lipid metabolism in focus: how the build-up and breakdown of lipids affects stem cells<\/a>. Madsen S*., Ramosaj M*. and Knobloch M. 2021\/27\/5. Development, 148 (10): dev191924. * first shared<\/p>\n\n\n\n

Stem Cell Reports, 2020<\/strong><\/h2>\n\n\n\n

A Single Metabolite which Modulates Lipid Metabolism Alters Hematopoietic Stem\/Progenitor Cell Behavior and Promotes Lymphoid Reconstitution. <\/a>Giger S., Kovtonyuk L.V., Utz S.G., Ramosaj M., Kovacs W.J., Schmid E., Ioannidis V., Greter M., Manz M.G., Lutolf M.P., Jessberger S., Knobloch, M. 2020\/09\/08. Stem Cell Reports, 3 (15) pp. 566-576.<\/p>\n\n\n\n

Scientific Reports, 2020<\/strong><\/h2>\n\n\n\n

A novel protocol to detect green fluorescent protein in unfixed, snap-frozen tissue. <\/a>Scandella V., Paolicelli R.C., Knobloch M., 2020\/09\/04. Scientific Reports, 10 (1) p. 14642.<\/p>\n\n\n\n

Cell Stem Cell, 2020<\/strong><\/h2>\n\n\n\n

Introductions to the Community: Early-Career Researchers in the Time of COVID-19.<\/a> Cell Stem Cell 2020 Jun 4;26(6):815-816. Epub 2020 May 20.<\/p>\n\n\n\n

Cell Stem Cell, 2019<\/strong><\/h2>\n\n\n\n

Sensing the Environment: Extracellular Lactate Levels Control Adult Neurogenesis<\/a>. Scandella V. & Knobloch M. 2019\/12\/05. Cell Stem Cell, 25 (6) pp. 729-731. Preview article<\/p>\n\n\n\n

Development, 2019<\/strong><\/h2>\n\n\n\n

A SY-Stematic approach towards understanding stem cell biology. <\/a>Pilz G.A. & Knobloch M., 2019\/06\/21. Development, 146 (13) pp. dev177220.<\/p>\n\n\n\n

Current Opinion in Lipidology, 2018<\/strong><\/h2>\n\n\n\n

Burning fat to keep your stem cells? The role of fatty acid oxidation in various tissue stem cells.<\/a> Knobloch M. & Widmann C., 2018\/10. Current Opinion in Lipidology, 29 (5) pp. 426-427.<\/p>\n\n\n\n

Nature, 2017<\/strong><\/h2>\n\n\n\n

The role of fatty acid \u03b2-oxidation in lymphangiogenesis. <\/a>Wong B.W., Wang X., Zecchin A., Thienpont B., Cornelissen I., Kalucka J., Garc\u00eda-Caballero M., Missiaen R., Huang H., Br\u00fcning U. et al., 2017\/02\/02. Nature, 542 (7639) pp. 49-54.<\/p>\n\n\n\n

Current Opinion in Neurobiology, 2017<\/strong><\/h2>\n\n\n\n

Metabolism and neurogenesis.<\/a> Knobloch M., Jessberger S., 2017\/02. Current opinion in neurobiology, 42 pp. 45-52.<\/p>\n\n\n\n

Brain Plasticity, 2017<\/strong><\/h2>\n\n\n\n

The Role of Lipid Metabolism for Neural Stem Cell Regulation.<\/a> Knobloch M., 2017. Brain Plasticity, 3 (1) pp. 61-71.<\/p>\n\n\n\n

Cell Reports, 2017<\/strong><\/h2>\n\n\n\n

A Fatty Acid Oxidation-Dependent Metabolic Shift Regulates Adult Neural Stem Cell Activity. <\/a>Knobloch M., Pilz G.A., Ghesqui\u00e8re B., Kovacs W.J., Wegleiter T., Moore D.L., Hruzova M., Zamboni N., Carmeliet P., Jessberger S., 2017. Cell Reports, 20 (9) pp. 2144-2155.<\/p>\n\n\n\n

Frontiers in Biology, 2015<\/strong><\/h2>\n\n\n\n

Metabolic control of adult neural stem cell behavior.<\/a> Knobloch M & Jessberger S, 2015\/04. Frontiers in Biology, 10 (2) pp. 100-106.<\/p>\n\n\n\n

Stem Cell Reports, 2014<\/strong><\/h2>\n\n\n\n

SPOT14-positive neural stem\/progenitor cells in the hippocampus respond dynamically to neurogenic regulators.<\/a> Knobloch M., von Schoultz C., Zurkirchen L., Braun S.M., Vidmar M., Jessberger S., 2014\/11\/11. Stem Cell Reports, 3 (5) pp. 735-742.<\/p>\n\n\n\n

Development, 2013<\/strong><\/h2>\n\n\n\n

Predicting stem cell fate changes by differential cell cycle progression patterns. <\/a>Roccio M., Schmitter D., Knobloch M., Okawa Y., Sage D., Lutolf M.P., 2013\/01\/15. Development, 140 (2) pp. 459-470.<\/p>\n\n\n\n

Nature, 2013<\/strong><\/h2>\n\n\n\n

Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis. <\/a>Knobloch M., Braun S.M., Zurkirchen L., von Schoultz C., Zamboni N., Ara\u00fazo-Bravo M.J., Kovacs W.J., Karalay O., Suter U., Machado R.A. et al., 2013\/01\/10. Nature, 493 (7431) pp. 226-230.<\/p>\n","protected":false},"excerpt":{"rendered":"

A complete list of publications can be found in Pubmed or on the University server IRIS. Here are the latest published articles displayed. Nature Cell Biology, 2026 Cellular…<\/p>\n","protected":false},"author":1002160,"featured_media":572,"parent":6,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"template-full-width-cover.php","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","footnotes":""},"class_list":["post-195","page","type-page","status-publish","has-post-thumbnail"],"_links":{"self":[{"href":"https:\/\/wp.unil.ch\/knobloch-lab\/wp-json\/wp\/v2\/pages\/195","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wp.unil.ch\/knobloch-lab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/wp.unil.ch\/knobloch-lab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/wp.unil.ch\/knobloch-lab\/wp-json\/wp\/v2\/users\/1002160"}],"replies":[{"embeddable":true,"href":"https:\/\/wp.unil.ch\/knobloch-lab\/wp-json\/wp\/v2\/comments?post=195"}],"version-history":[{"count":5,"href":"https:\/\/wp.unil.ch\/knobloch-lab\/wp-json\/wp\/v2\/pages\/195\/revisions"}],"predecessor-version":[{"id":1372,"href":"https:\/\/wp.unil.ch\/knobloch-lab\/wp-json\/wp\/v2\/pages\/195\/revisions\/1372"}],"up":[{"embeddable":true,"href":"https:\/\/wp.unil.ch\/knobloch-lab\/wp-json\/wp\/v2\/pages\/6"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/wp.unil.ch\/knobloch-lab\/wp-json\/wp\/v2\/media\/572"}],"wp:attachment":[{"href":"https:\/\/wp.unil.ch\/knobloch-lab\/wp-json\/wp\/v2\/media?parent=195"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}