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April 2021


DBC News is a monthly publication that seeks to inform first and foremost faculty members, researchers and students. It also reaches out to a wider community - Department of Computaional Biology partners, esteemed visiting faculty and friends.

Alongside the Department's website it is a complementary means of keeping abreast of the Department's rich and diversified scientific activities - visiting faculty, exceptional conferences, publications, awards, appointments, calls for papers and research, ...


The whole DBC extends the warmest of welcomes to new members.
NZ Photo Newsletter
Natalia Zajac
Post-Doctoral student, Group Dessimoz

I did my PhD at ETH Zurich in the group of Prof. Jukka Jokela. I worked on the genomics of adaptation of a trematode parasite Atriophallophorus winterbourni to its snail host, both over macroevolutionary scales (using comparative genomics methods) and microevolutionary scales (using population genomics methods). I will be joining the group of Prof. Christophe Dessimoz to work on the evolution of genome architecture focusing on gene synteny in trematode parasites.



Many thanks to all of you for the good collaboration throughout these years and we all wish every success in your future endeavours.
Dr. Frédérique Varoqueaux
Senior Researcher - Group Fasshauer
Neveu E. 7665
Emilie Neveu
Postdoctoral position, Group Fasshauer


Do you feel like a banana today?

This may be normal because some say that humans share 50% of their DNA with bananas!

What ?! How?! Why?!

So many questions to which Prof. Christophe Dessimoz and Dr. Natasha Glover answer through computational biology.

And what else can computational biology do for you? Can it help better monitor the progress of the current epidemic?
All the answers are in the CQFD show, to listen to urgently!

In this presentation, Dr. Lê Nguyên Hoang will share his background in scientific communication, as well as tips for successful communication

After obtaining a engineering degree from the École Polytechnique in Paris, Lê Nguyên Hoang received a PhD from Polytechnique Montreal, and then became a postdoctoral research at the Massachusetts Institute of Technology (MIT). He then became a computer science researcher and a science communicator at the École polytechnique fédérale de Lausanne (EPFL). He also runs the YouTube channel Science4All, with 200k+ subscribers. He authored the books "The equation of knowledge", "Le fabuleux chantier" (with El Mahdi El Mhamdi) and "Turing à la plage" (with Rachid Guerraoui). More recently, he co-invented, a platform for collaborative content recommendation

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Capture d’écran 2021-03-24 à 15.02.00

The [BC]2 Basel Computational Biology Conference provides a unique platform to scientists at all career stages to present their research. It unites researchers from academia, industry and healthcare working in a broad range of disciplines: from deciphering spatiotemporal gene expression patterns, to modelling evolutionary dynamics or acquiring a better understanding of how genetics influence human health.
Learn more

For more Research news and infos on DBC Events, please check out the DBC Website

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What follows is a small sampling of recently published research across the department — for a more complete list of publications, visit PubMed. If there is a paper you would like to see highlighted in the next issue of the newsletter, please email us.
Gene Duplication and Gain in the Trematode Atriophallophorus winterbourni Contributes to Adaptation to Parasitism - With Natalia Zajac, David Moi, Christophe Dessimoz, Natasha Glover

On the Effect of Asymmetrical Trait Inheritance on Models of Trait Evolution -
With Pablo Duchen, Jonathan Rolland, Nicolas Salamin, Daniele Silvestro

Non-genetic evolution drives lung adenocarcinoma spatial heterogeneity and progression
With Daniele Tavernari, Elena Battistello, Marco Mina, David Gfeller, Giovanni Ciriello

Prediction of neo-epitope immunogenicity reveals TCR recognition determinants and provides insight into immunoediting
With Giovanni Ciriello, David Gfeller

Sustained androgen receptor signaling is a determinant of melanoma cell growth potential and tumorigenesis
With Daniele Tavernari, Giovanni Ciriello

Phylogenomics of Gesneriaceae using targeted capture of nuclear genes
With Nicolas Salamin

Choanoflagellates and the ancestry of neurosecretory vesicles
With Frédérique Varoqueaux, Dirk Fasshauer


PhD position in David Gfeller's lab

Postdoctoral position in Quantitative Genetics

Postdoc in Computational Structural Biology (HPC enabled computer-aided drug discovery)

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