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DBC News is a monthly publication that seeks to inform first and foremost faculty members, researchers and students. It also reaches out to a wider community - Department of Computational Biology partners, visiting faculty and friends.
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Alongside the Department's website it is a complementary means of keeping abreast of the Department's rich and diversified scientific activities - visiting faculty, exceptional conferences, publications, awards, appointments, calls for papers and research, ...
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The whole DBC extends the warmest of welcomes to new members.
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I'm thrilled to rejoin Bergmann's group as a Junior Researcher in order to further explore the associations between physiological factors and external and retinal eye image.
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Miren joined Malaspinas’ group to work on population genomic projects, with a primary focus on the Mediterranean region after the Bronze Age.
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"Spatial inference of population structure, prehistoric human mobility and relatedness from ancient human genomes"
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Leader Researcher at Institut de Biologie de l'École Normale Supérieure (IBENS).
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"Imbalanced diversification pulses sustain the rise, decline and fall of clades"
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February 6th – February 7th - Lausanne (Gen)Omics Days 2025
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The Lausanne Genomics Days is a 2-day international conference meant to share advances in (Gen)Omics and their impact on biological research, applied to a wide range of topics.
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February 12th - SDM-CH: Modelling species distributions in Switzerland for science and practice
Are you interested in modeling species distribution in Switzerland for science and applications? Join the SDM-CH symposium to learn more about existing tools and predictions in Switzerland, as well as ongoing projects and future needs.
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Biology25 conference -
February 13-14
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Biology25 is the largest conference dedicated to organismal biology in Switzerland and serves as the annual joint meeting of the Swiss Zoological Society, the Swiss Botanical Society, and the Swiss Systematics Society. It offers a great opportunity for PhD students and early-career researchers to showcase their research.
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July 27-31st - Leena Peltonen School of Human Genetics summer school
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This prestigious summer school brings together 20 leaders in human genetics with 20 students close to their PhD completion. This isn't just a course; it's a science summer camp designed for in-depth exploration of the future of genomics through vibrant discussions and debates, with the participation of amazing researchers such as Prof. Zoltán Kutalik.
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📅 When? : July 27-31, 2025
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📍 Where? : Wellcome Genome Campus, Hinxton, UK
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📝 Application deadline : March 7, 2025
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How do scientists find genes using computers?
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Where to find your DNA in the Genes?
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All the events of the APNS here
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What follows is a small sampling of recently published research across the department — for a more complete list of publications, visit PubMed. If there is a paper you would like to see highlighted in the next issue of the newsletter, please email us.
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- With Thibault Latrille, Diego A. Hartasánchez and Nicolas Salamin
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Beneficial mutations can either adapt organisms to environmental changes or restore lost fitness due to genetic drift. This study shows that non-adaptive beneficial mutations, which are often overlooked, significantly contribute to positive selection in mammals.
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A genome-wide association study on income among Europeans identified 162 genomic loci linked to income, with small effect sizes. The study found genetic correlations with educational attainment and health, showing complex genetic influences on income and health disparities.
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Six novel Bifidobacterium strains were isolated from the honey stomach of Apis mellifera. These strains are Gram-positive, non-motile, non-sporulating, and facultatively anaerobic. Genetic analysis revealed that some strains are closely related to Bifidobacterium polysaccharolyticum, while others are related to Bifidobacterium apousia. Phenotypic and genotypic characterization confirmed that strain H1HS16NT represents a novel species, proposed as Bifidobacterium kimbladii sp. nov.
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We propose graph alignment and our new algorithm, bamRefine, to minimize reference bias and postmortem damage in low coverage paleogenomes. These methods effectively reduce bias and damage, starting from raw read files, and we recommend publishing FASTQ files.
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Quality assessment of gene repertoire annotations with OMark - With Yannis Nevers, Alex Warwick Vesztrocy , Victor Rossier, Clément-Marie Train, Adrian Altenhoff, Christophe Dessimoz and Natasha M. Glover
This study proposes graph alignment and our new algorithm, bamRefine, to minimize reference bias and postmortem damage in low coverage paleogenomes. These methods effectively reduce bias and damage, starting from raw read files, and we recommend publishing FASTQ files.
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Are you an alumnus or former employee of the department? Email us your news and updates to include in an upcoming newsletter!
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