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December 2024

Newsletter

DBC News is a monthly publication that seeks to inform first and foremost faculty members, researchers and students. It also reaches out to a wider community - Department of Computational Biology partners, visiting faculty and friends.

Alongside the Department's website it is a complementary means of keeping abreast of the Department's rich and diversified scientific activities - visiting faculty, exceptional conferences, publications, awards, appointments, calls for papers and research, ...
✨✨ As the festive season approaches, we want to take a moment to express our deep appreciation for all the hard work and dedication shown by every member of the DBC this year. Your contributions have been invaluable. Wishing you joyous holidays filled with health, happiness, and peace. May you and your loved ones enjoy a wonderful and memorable festive season. ✨✨

WELCOME

The whole DBC extends the warmest of welcomes to new members.

Florentin Constancias
Researcher, Group Lehtinen

Florentin is a computational microbial ecologist specialized in microbial communities in both environmental and host-associated habitats.

Learn more

CONGRATULATIONS!


Congratulations Dr. Sara Heim on the successful completion of her PhD!!


Sara's thesis, titled “Revealing the clownfish - sea anemone chemical mutualism through the skin mucus”, has encompassed research on the metabolomics and transcriptomics analyses of the adaptation of clownfishes to sea anemone.

DBC NEWS

January 23rd - DBC Seminar
with Dr. Katalin Csilléry


Leader of the Evolutionary Genetics Group - Swiss Federal Research Institute WSL

January 30th - DBC Seminar
with Dr. Meike Ramon

Assistant Professor and Swiss National Science Foundation PRIMA (Promoting Women in Academia) Fellow - AFC Lab

EDUCATION AND OUTREACH

How do scientists find genes using computers?

Where to find your DNA in the Genes?
Find out with Silvia Prieto Baños, Phd student in the Dessimoz's lab.
Watch the video,
For more videos, visit the DBC YouTube channel and subscribe

EXPLORE MORE...

For more Research news and infos on DBC Events, please check out the DBC Website

Check out
CIG News
SIB News
Skills for Scientists

All the events of the APNS here

RESEARCH HIGHLIGHTS

What follows is a small sampling of recently published research across the department — for a more complete list of publications, visit PubMed. If there is a paper you would like to see highlighted in the next issue of the newsletter, please email us.

Lipid disturbances induced by psychotropic drugs: clinical and genetic predictors for early worsening of lipid levels and new-onset dyslipidaemia in Swiss psychiatric samples
With Marie Sadler, Zoltan Kutalik - The study aimed to identify clinical and genetic risk factors predicting early worsening of plasma lipid levels (EWL) in patients on psychotropic treatments. It found that low baseline cholesterol and triglyceride levels, and high HDL-C levels, were risk factors for EWL. Adding genetic data improved the prediction accuracy for EWL and new-onset dyslipidaemia.
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Identification of rare disease genes as drivers of common diseases through tissue-specific gene regulatory networksWith Marie Sadler, Zoltan Kutalik
The study explores how common genetic variants, identified through GWAS, influence gene co-expression across various tissues, linking them to rare Mendelian diseases. Using the Downstreamer framework, the researchers found that many key genes associated with common traits, like height, are also linked to Mendelian diseases. These genes often lie outside GWAS loci, indicating complex regulatory mechanisms. The findings highlight challenges in mapping gene networks and suggest ways to better identify genes connected to common diseases.
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Psychotropic-induced weight gain and telomere length: results from a one-year longitudinal study and a large population-based cohort - With Zoltan Kutalik
The study found that weight-inducing psychotropic treatments lead to significant telomere shortening over one year, especially in patients with low baseline weight and significant weight gain. Increased BMI and higher CRP levels were associated with greater telomere shortening, indicating a link between weight gain, inflammation, and accelerated cellular aging.

Explore more...

JOB OPENINGS

Two Tenure-Track Assistant Professorships in Computer Science at Bocconi University - Location : Milan, Italy

Postdoctoral Research Position - Location : Bremen, Germany

Postdoctoral position in bioinformatics and biostatistics (scholarship) -
Location
: Stockholm, Sweden

ALUMNI SPOTLIGHT

Are you an alumnus or former employee of the department? Email us your news and updates to include in an upcoming newsletter!