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May 2022

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WELCOME !

The whole DBC extends the warmest of welcomes to new members.
Charles Bernard,
Postdoc Groupe Dessimoz

After a B.A. in Bioinformatics and a M.A. in Computational & Systems Biology at the Center for Interdisciplinary Research in Paris, I worked for one year as a bioinformatician in the lab of Fatima Mechta-Grigoriou at the Curie Institute for cancer research in Paris. There, using scRNA-seq data analysis, I investigated the link between fibroblasts heterogeneity and immunotherapy resistance in breast cancer. Wishing to refocus on evolutionary bioinformatics, I then joined the labs of Eric Bapteste, Philippe Lopez and Yanyan Li at the National Museum of Natural History of Paris for a PhD during which I explored the phylogenetic and functional diversity of quorum sensing communication systems in bacterial chromosomes, plasmids and bacteriophage genomes. I’m now joining with great enthusiasm the lab of Christophe Dessimoz for a Post-Doc during which I will use comparative genomics between prokaryotes (and even viruses) to reconstruct ancestral syntenies. This will notably help uncovering unprecedented evolutionary conserved modules of genes of interest, like novel defense systems in bacteria.

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