{"id":6,"date":"2019-11-28T16:00:19","date_gmt":"2019-11-28T15:00:19","guid":{"rendered":"http:\/\/wp.unil.ch\/modele\/?page_id=6"},"modified":"2026-10-23T15:52:41","modified_gmt":"2026-10-23T13:52:41","slug":"home","status":"publish","type":"page","link":"https:\/\/wp.unil.ch\/cbg\/","title":{"rendered":"Computational Biology Group"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">The&nbsp;<strong>Computational Biology Group (CBG)<\/strong>, led by Prof. Sven Bergmann, is part of the Department of Computational Biology at the University of Lausanne and affiliated with the&nbsp;<a href=\"https:\/\/www.sib.swiss\/fr\/sven-bergmann-group\" target=\"_blank\" rel=\"noopener\">Swiss Institute of Bioinformatics<\/a>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">We develop and apply computational methods, ranging from statistical approaches to machine learning, to understand how genetic variation shapes complex biological phenotypes and human disease. Our research combines&nbsp;<strong>genomics, medical imaging and large-scale population data<\/strong>, with the aim of uncovering biological mechanisms and improving our understanding and prediction of human disease.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A major current focus is&nbsp;<strong>image-based phenotyping<\/strong>. We use medical images \u2014 particularly retinal images, but also images of other organs and vascular structures \u2014 to derive quantitative phenotypes using both interpretable image features and deep-learning models.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Our current research builds on longstanding interests in&nbsp;<strong>statistical genetics, systems biology and computational genomics<\/strong>, ranging from the analysis and integration of high-dimensional molecular data to modelling biological systems.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Close collaborations with geneticists, clinicians, imaging specialists and other computational scientists are an integral part of our research.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1536\" height=\"1024\" src=\"https:\/\/wp.unil.ch\/cbg\/files\/2026\/10\/databio_bergmann_svg-2.svg\" alt=\"databio bergmann svg 2\" class=\"wp-image-278\" \/><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>The&nbsp;Computational Biology Group (CBG), led by Prof. Sven Bergmann, is part of the Department of Computational Biology at the University of Lausanne and affiliated with the&nbsp;Swiss Institute of Bioinformatics. We develop and apply computational methods, ranging from statistical approaches to machine learning, to understand how genetic variation shapes complex biological phenotypes and human disease. Our [&hellip;]<\/p>\n","protected":false},"author":108,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","_seopress_robots_follow":"","_seopress_robots_imageindex":"","_seopress_robots_snippet":"","_seopress_robots_primary_cat":"","_seopress_robots_breadcrumbs":"","_seopress_robots_freeze_modified_date":"","_seopress_robots_custom_modified_date":"","_seopress_robots_canonical":"","_seopress_social_fb_title":"","_seopress_social_fb_desc":"","_seopress_social_fb_img":"","_seopress_social_fb_img_attachment_id":0,"_seopress_social_fb_img_width":0,"_seopress_social_fb_img_height":0,"_seopress_social_twitter_title":"","_seopress_social_twitter_desc":"","_seopress_social_twitter_img":"","_seopress_social_twitter_img_attachment_id":0,"_seopress_social_twitter_img_width":0,"_seopress_social_twitter_img_height":0,"_seopress_redirections_value":"","_seopress_redirections_enabled":"","_seopress_redirections_enabled_regex":"","_seopress_redirections_logged_status":"","_seopress_redirections_param":"","_seopress_redirections_type":0,"_seopress_analysis_target_kw":"","_seopress_news_disabled":"","_seopress_video_disabled":"","_seopress_video":[],"_seopress_pro_schemas_manual":[],"_seopress_pro_rich_snippets_disable_all":"","_seopress_pro_rich_snippets_disable":[],"_seopress_pro_schemas":[],"footnotes":""},"class_list":["post-6","page","type-page","status-publish"],"_links":{"self":[{"href":"https:\/\/wp.unil.ch\/cbg\/wp-json\/wp\/v2\/pages\/6","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wp.unil.ch\/cbg\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/wp.unil.ch\/cbg\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/wp.unil.ch\/cbg\/wp-json\/wp\/v2\/users\/108"}],"replies":[{"embeddable":true,"href":"https:\/\/wp.unil.ch\/cbg\/wp-json\/wp\/v2\/comments?post=6"}],"version-history":[{"count":4,"href":"https:\/\/wp.unil.ch\/cbg\/wp-json\/wp\/v2\/pages\/6\/revisions"}],"predecessor-version":[{"id":279,"href":"https:\/\/wp.unil.ch\/cbg\/wp-json\/wp\/v2\/pages\/6\/revisions\/279"}],"wp:attachment":[{"href":"https:\/\/wp.unil.ch\/cbg\/wp-json\/wp\/v2\/media?parent=6"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}