For guidelines and policies related to blood analyses, please refer to the specific pages on our web site. For metabolic analyses, please read below.
Application for Services
Concepts and practical aspects of the tests are found under Test & Services. After identifying the appropriate test(s), the applicant is invited to contact the MEF supervisor (Frederic.Preitner@unil.ch). A discussion meeting between the MEF supervisor and the requesting laboratory is called to decide on the final strategy and provide a cost estimate. At this point, the Principal Investigator of the requesting laboratory confirms his agreement by email, and a schedule is planned for the test. Applications should be sent several weeks prior the experiments.
The MEF personel aims at providing access to the largest number of applicants possible. Therefore, decisions to perform labor-intensive experiments (“secondary screen”) will rely on experimental data obtained by rapid analyses (“primary screen”) performed beforehand by the applicant or at the MEF.
Priority access is on a “first come-first served” basis. Therefore, last-minute requests might be honored with a significant delay. However, the MEF supervisor has some flexibility towards priority access, which might depend on practical aspects. The laboratory requesting service of the MEF agrees to provide the required animals for the planned experiments, and to pay the MEF the appropriate fees. The applicant also acknowledges and accepts that the final price and total number of animals required to complete the test may vary according to difficulties encountered specifically with some rodent models.
Before sending mice to the MEF, Please make sure to fulfill all following requirements.
- Animal experimentation Authorizations (e-tierversuche): Prior to any mouse experiment at MEF, all animal study protocols must be approved by the Canton Veterinary Office (SCAV). Experimental protocols to be detailed in the authorization requests (e-tierversuche) can be found under Protocols.
- Health status reports for the past 12 months : Health status reports (related to the specific rooms that host the mice to be sent to MEF) must be obtained by the applicant from the head of his Institute’s animal core facility and sent to Dr Frederic Preitner for evaluation one week prior shipment of the animals. Please contact us for shipping and handling guidelines.
- Mice inventory in PyRat: All animal facilities in Lausanne use the same mouse inventory online system (PyRat). For all Mice to be hosted at MEF:
- Applicant researchers from UNIL/CHUV: please ask your local PyRat administrator (usually the head of your animal core facility) to modify your mice information in PyRat as follows: transfer the ownership of the mice to MEF-Fred. Then, relocate the mice from your facility to the MEF, usually to rack nb. 7 (please ask us for confirmation).
- Applicants outside of Lausanne: Please provide us with the official name of your mouse strain (using approved nomenclature), and all general information (gender, birth date, strain, number of mice). Our administrator will create a new entry for your line in PyRat. Only afterwards can you send us the mice.
Data and Data Ownership
All data will be processed, presented in an appropriate way and sent as an electronic document to the applicant. The MEF personnel will be available to discuss various aspects of the test, including experimental details and interpretation of the results.
All data generated upon request in the MEF strictly belong to the applicant investigator and his institution. Thus, this data cannot be used by the MEF personnel for personal or institutional research purposes unless a formal, written agreement of collaboration is established between MEF personnel and the investigator.
The MEF personnel and the investigator must read and sign a Mouse/Tissue transfer agreement that clearly defines rights and responsibilities of each part.
Price information is available for each test on the Tests & Services web pages. A written estimate of the fees must be agreed on by the applicant before animals are shipped to the Center.
Fees indicated for each test under Tests & Services apply to the Cardiomet Academic Partners and are set at a fraction of the total cost of the tests. For private companies and biotech firms, access to the Cardiomet service is charged at full cost (please request pricing).
Acknowledgements & Authorship
Investigators are expected to acknowledge the use of the MEF in their publications. In addition, whenever time-consuming, labor-intensive experiments and/or that require substantial scientific input are performed, the contribution of the MEF staff should be recognized as a scientific collaboration, and involved MEF collaborators will be authors in resulting publications, in addition to the fees.