New lab publication in Nature

Check our new publication in Nature. We show that the polarity factor Pom1 acts as an inhibitor of mitotic entry, upstream of Wee1 kinase. Pom1 negatively regulates the kinase Cdr2, itself an inhibitor of Wee1. As Pom1 forms concentration gradients from cell poles, and Cdr2 localizes at the medial cortex, this regulatory network may allow cells to measure their own length and delay division until they reach sufficient size. The press release from the University of Lausanne can be found here.