Lab News

Drilling down on OPS function

New research from our lab in collaboration with Ruediger Simon’s group at Heinrich-Heine University Duesseldorf, Germany, suggests that the enigmatic OPS protein interferes with CLE45 signaling by directly disturbing the interactions of CLE45 receptor components. Highlighting the exquisitely quantitative aspect of OPS action, a genetic game combining higher or lower OPS activity with higher or lower CLE45 pathway activity demonstrates the in vivo relevance of our findings. Find the full paper published Open Access here.