Category Archives: evolution

Coregulation of tandem duplicate genes slows evolution of subfunctionalization in mammals

Gene duplications are main contributors of genome evolution, but most of the duplicates are redundant and go through pseudogenization. There are several mechanisms proposed to explain how young duplicates survive long-term and escape from being degraded. Among these, dosage-balance model … Continue reading

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Peppered moth melanism mutation is a transposable element

One of the most known examples of natural selection in action is the evolution of the peppered moth (Biston betularia), the rapid replacement of the light-colored form of the moth (typica) by a dark-colored form (carbonaria) (Fig. 1) during 1800s … Continue reading

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ExAC presents a catalogue of human protein-coding genetic variation

Exploration of variability of human genomes represents a key step in the holy grail of human genetics – to link genotypes with phenotypes, it also provides insights to human evolution and history. For this purpose Exome Aggregation Consortium (ExAC) have … Continue reading

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Supergenes and social organization in a bird species

      Cindy Dupuis, Xinji Li, Casper van der Kooi   The development of new molecular mechanisms and next generation sequencing techniques have advanced our knowledge on the genetic basis underlying phenotypic polymorphism. Over the coarse of recent years, … Continue reading

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Evolution of Darwin’s finches and their beaks revealed by genome sequencing

Introduction Darwin’s finches from Galapagos and Cocos Island are classic example of young adaptive radiation, entirely intact because none of the species having become extinct as a result of human activity. They have diversified in beak sizes and shapes, feeding … Continue reading

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The genomic substrate for adaptive radiation in African cichlid fish

In African lakes, cichlid fishes are famous for large, diverse and replicated adaptive radiations. Nearly 1,500 new species of cichlid fish evolved in a few million years when environmentally determined opportunity for sexual selection and ecological niche expansion was met … Continue reading

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The genomic landscape underlying phenotypic integrity in the face of gene flow in crows

The role of interspecific gene flow in species diversification has long been debated and is increasingly appreciated. However, the effect of gene introgression on phenotypic divergences and genome heterogeneity remain unclear in case of early speciation. To investigate these questions … Continue reading

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Crossovers are associated with mutation and biased gene conversion at recombination hotspots

Meiosis is an important biological process by which combination of various types of the genes called alleles, are segregated and packed in each germ cell waiting to be transferred and expressed in descendants. This combinations of alleles are products of … Continue reading

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Evolution at two levels of gene expression in yeast

Protein abundances mainly determined by the balance of transcriptional and translational regulation. Because of the limited technology for the translational research, however, gene expression evolution was based almost entirely on studies of transcriptional regulation. With the quickly development of ribosome profiling–isolating and … Continue reading

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Convergent evolution of the genomes of marine mammals

Convergent evolution is defined by the independent evolution of similar traits in different lineages, in order to adapt to similar environmental conditions. Examples of this phenomenon include adaptations to altitude in humans, independent evolution of flight in birds and bats … Continue reading

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