Publications

Listening to the Patient Voice in Narcolepsy: Diagnostic Delay, Disease Burden, and Treatment Efficacy.
Maski K, Steinhart E, Williams D, Scammell T, Flygare J, McCleary K, Gow M.
J Clin Sleep Med. 2016 Nov 28. pii: jc-00295-16. [Epub ahead of print]
PMID: 27923434

Understanding the needs of older patients with narcolepsy.
Krahn LE.
Sleep Med. 2016 Sep 30. pii: S1389-9457(16)30150-2. doi: 10.1016/j.sleep.2016.08.010. [Epub ahead of print]
PMID: 27887886

High Rates of Psychiatric Comorbidity in Narcolepsy: Findings From the Burden of Narcolepsy Disease (BOND) Study of 9,312 Patients in the United States.
Ruoff CM, Reaven NL, Funk SE, McGaughey KJ, Ohayon MM, Guilleminault C, Black J.
J Clin Psychiatry. 2016 Nov 8. doi: 10.4088/JCP.15m10262. [Epub ahead of print]
PMID: 27835717

Body weight and basal metabolic rate in childhood narcolepsy: a longitudinal study.
Wang Z, Wu H, Stone WS, Zhuang J, Qiu L, Xu X, Wang Y, Zhao Z, Han F, Zhao Z.
Sleep Med. 2016 Sep;25:139-144. doi: 10.1016/j.sleep.2016.06.019.
PMID: 27823707

High-dimensional single-cell analysis reveals the immune signature of narcolepsy.
Hartmann FJ, Bernard-Valnet R, Quériault C, Mrdjen D, Weber LM, Galli E, Krieg C, Robinson MD, Nguyen XH, Dauvilliers Y, Liblau RS, Becher B.
J Exp Med. 2016 Nov 14;213(12):2621-2633.
PMID: 27821550

Impact of sodium oxybate, modafinil, and combination treatment on excessive daytime sleepiness in patients who have narcolepsy with or without cataplexy.
Black J, Swick T, Bogan R, Lai C, Carter LP.
Sleep Med. 2016 Aug;24:57-62. doi: 10.1016/j.sleep.2016.07.010.
PMID: 27810187 Free Article

Effect of sodium oxybate on disrupted nighttime sleep in patients with narcolepsy.
Roth T, Dauvilliers Y, Guinta D, Alvarez-Horine S, Dynin E, Black J.
J Sleep Res. 2016 Nov 3. doi: 10.1111/jsr.12468. [Epub ahead of print]
PMID: 27807903

Insomnia, parasomnias, and narcolepsy in children: clinical features, diagnosis, and management.
Maski K, Owens JA.
Lancet Neurol. 2016 Oct;15(11):1170-81. doi: 10.1016/S1474-4422(16)30204-6. Review.
PMID: 27647645

CD8 T cell-mediated killing of orexinergic neurons induces a narcolepsy-like phenotype in mice.
Bernard-Valnet R, Yshii L, Quériault C, Nguyen XH, Arthaud S, Rodrigues M, Canivet A, Morel AL, Matthys A, Bauer J, Pignolet B, Dauvilliers Y, Peyron C, Liblau RS.
Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):10956-61. doi: 10.1073/pnas.1603325113.
PMID: 27621438

Patterns of spontaneous reports on narcolepsy following administration of pandemic influenza vaccine; a case series of individual case safety reports in Eudravigilance.
Gadroen K, Straus SM, Pacurariu A, Weibel D, Kurz X, Sturkenboom MC.
Vaccine. 2016 Sep 22;34(41):4892-7. doi: 10.1016/j.vaccine.2016.08.062.
PMID: 27577558

Aberrant Food Choices after Satiation in Human Orexin-Deficient Narcolepsy Type 1.
van Holst RJ, van der Cruijsen L, van Mierlo P, Lammers GJ, Cools R, Overeem S, Aarts E.
Sleep. 2016 Nov 1;39(11):1951-1959.
PMID: 27568806

Efficiency of a Combination of Pharmacological Treatment and Nondrug Interventions in Childhood Narcolepsy.
Kacar Bayram A, Per H, Ismailoğullari S, Canpolat M, Gumus H, Aksu M.
Neuropediatrics. 2016 Dec;47(6):380-387.
PMID: 27564079

Comorbidity of Narcolepsy Type 1 With Autoimmune Diseases and Other Immunopathological Disorders: A Case-Control Study.
Martinez-Orozco FJ, Vicario JL, De Andres C, Fernandez-Arquero M, Peraita-Adrados R.
J Clin Med Res. 2016 Jul;8(7):495-505. doi: 10.14740/jocmr2569w.
PMID: 27298657 Free PMC Article

Treatment Options for Narcolepsy.
Barateau L, Lopez R, Dauvilliers Y.
CNS Drugs. 2016 May;30(5):369-79. doi: 10.1007/s40263-016-0337-4.
PMID: 27155860

Prescribing sodium oxybate for narcolepsy.
Zeman A, Zaiwalla Z.
BMJ. 2016 Apr 28;353:i2367. doi: 10.1136/bmj.i2367. No abstract available.
PMID: 27126864

The hypocretin/orexin system in sleep disorders: preclinical insights and clinical progress.
Chow M, Cao M.
Nat Sci Sleep. 2016 Mar 14;8:81-6. doi: 10.2147/NSS.S76711. Review.
PMID: 27051324

Cerebrospinal Fluid Hypocretin-1 (Orexin-A) Level Fluctuates with Season and Correlates with Day Length.
Boddum K, Hansen MH, Jennum PJ, Kornum BR.
PLoS One. 2016 Mar 23;11(3):e0151288. doi: 10.1371/journal.pone.0151288.
PMID: 27008404 Free PMC Article

Disrupted Sleep in Narcolepsy: Exploring the Integrity of Galanin Neurons in the Ventrolateral Preoptic Area.
Gavrilov YV, Ellison BA, Yamamoto M, Reddy H, Haybaeck J, Mignot E, Baumann CR, Scammell TE, Valko PO.
Sleep. 2016 May 1;39(5):1059-62. doi: 10.5665/sleep.5754.
PMID: 26951397 Free PMC Article

Improved vigilance after sodium oxybate treatment in narcolepsy: a comparison between in-field and in-laboratory measurements.
van Schie MK, Werth E, Lammers GJ, Overeem S, Baumann CR, Fronczek R.
J Sleep Res. 2016 Aug;25(4):486-96. doi: 10.1111/jsr.12386.
PMID: 26909768

Dante Alighieri’s narcolepsy.
Galassi FM, Habicht ME, Rühli FJ.
Lancet Neurol. 2016 Mar;15(3):245. doi: 10.1016/S1474-4422(16)00029-6. No abstract available.
PMID: 26888352

The European Narcolepsy Network (EU-NN) database.
Khatami R, Luca G, Baumann CR, Bassetti CL, Bruni O, Canellas F, Dauvilliers Y, Del Rio-Villegas R, Feketeova E, Ferri R, Geisler P, Högl B, Jennum P, Kornum BR, Lecendreux M, Martins-da-Silva A, Mathis J, Mayer G, Paiva T, Partinen M, Peraita-Adrados R, Plazzi G, Santamaria J, Sonka K, Riha R, Tafti M, Wierzbicka A, Young P, Lammers GJ, Overeem S; European Narcolepsy Network..
J Sleep Res. 2016 Jun;25(3):356-64. doi: 10.1111/jsr.12374.
PMID: 26809504

H1N1 infection of sleep/wake regions results in narcolepsy-like symptoms.
Black SW, Kilduff TS.
Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):476-7. doi: 10.1073/pnas.1524150113. No abstract available.
PMID: 26747601 Free PMC Article

H1N1 influenza virus induces narcolepsy-like sleep disruption and targets sleep-wake regulatory neurons in mice.
Tesoriero C, Codita A, Zhang MD, Cherninsky A, Karlsson H, Grassi-Zucconi G, Bertini G, Harkany T, Ljungberg K, Liljeström P, Hökfelt TG, Bentivoglio M, Kristensson K.
Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):E368-77. doi: 10.1073/pnas.1521463112.
PMID: 26668381 Free PMC Article

Narcolepsy-Associated HLA Class I Alleles Implicate Cell-Mediated Cytotoxicity.
Tafti M, Lammers GJ, Dauvilliers Y, Overeem S, Mayer G, Nowak J, Pfister C, Dubois V, Eliaou JF, Eberhard HP, Liblau R, Wierzbicka A, Geisler P, Bassetti CL, Mathis J, Lecendreux M, Khatami R, Heinzer R, Haba-Rubio J, Feketeova E, Baumann CR, Kutalik Z, Tiercy JM.
Sleep. 2016 Mar 1;39(3):581-7. doi: 10.5665/sleep.5532.
PMID: 26518595 Free PMC Article

DQB1 locus alone explains most of the risk and protection in narcolepsy with cataplexy in Europe.
Tafti M, Hor H, Dauvilliers Y, Lammers GJ, Overeem S, Mayer G, Javidi S, Iranzo A, Santamaria J, Peraita-Adrados R, Vicario JL, Arnulf I, Plazzi G, Bayard S, Poli F, Pizza F, Geisler P, Wierzbicka A, Bassetti CL, Mathis J, Lecendreux M, Donjacour CE, van der Heide A, Heinzer R, Haba-Rubio J, Feketeova E, Högl B, Frauscher B, Benetó A, Khatami R, Cañellas F, Pfister C, Scholz S, Billiard M, Baumann CR, Ercilla G, Verduijn W, Claas FH, Dubois V, Nowak J, Eberhard HP, Pradervand S, Hor CN, Testi M, Tiercy JM, Kutalik Z.
Sleep. 2014 Jan 1;37(1):19-25.

A patient with narcolepsy with cataplexy and multiple sclerosis: two different diseases that may share pathophysiologic mechanisms?
Peraita-Adrados R, Lammers GJ, De Andrés C, Santamaría J, Vicario JL, Tafti M.
Sleep Med. 2013 [Epub ahead of print]

Electroencephalogram paroxysmal theta characterizes cataplexy in mice and children.
Vassalli A, Dellepiane JM, Emmenegger Y, Jimenez S, Vandi S, Plazzi G, Franken P, Tafti M.
Brain. 2013; 136:1592-608

Clinical, polysomnographic and genome-wide association analyses of narcolepsy with cataplexy: a European Narcolepsy Network study.
Luca G, Haba-Rubio J, Dauvilliers Y, Lammers GJ, Overeem S, Donjacour CE, Mayer G, Javidi S, Iranzo A, Santamaria J, Peraita-Adrados R, Hor H, Kutalik Z, Plazzi G, Poli F, Pizza F, Arnulf I, Lecendreux M, Bassetti C, Mathis J, Heinzer R, Jennum P, Knudsen S, Geisler P, Wierzbicka A, Feketeova E, Pfister C, Khatami R, Baumann C, Tafti M; European Narcolepsy Network (EU-NN).
J Sleep Res. 2013 doi: 10.1111/jsr.12044. [Epub ahead of print]

Maurovich Horvat E, et al.Narcolepsy and pregnancy: a retrospective European evaluation of 249 pregnancies. J Sleep Research 2013; Apr 8. doi: 10.1111/jsr.1

Lecendreux M, Bruni O, Franco P, Gringras P, Konofal E, Nevsimalova S, Paiva T, Partinen M, Peeters E, Peraita-Adrados R, Plazzi G, Poli F. Clinical experience suggests that modafinil is an effective and safe treatment for paediatric narcolepsy.J Sleep Res. 2012; 21(4):481-3.

A missense mutation in myelin oligodendrocyte glycoprotein as a cause of familial narcolepsy with cataplexy.
Hor H, Bartesaghi L, Kutalik Z, Vicário JL, de Andrés C, Pfister C, Lammers GJ, Guex N, Chrast R, Tafti M, Peraita-Adrados R.
Am J Hum Genet. 2011;89(3):474-9.

Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy.
Hor H, Kutalik Z, Dauvilliers Y, Valsesia A, Lammers GJ, Donjacour CE, Iranzo A, Santamaria J, Peraita Adrados R, Vicario JL, Overeem S, Arnulf I, Theodorou I, Jennum P, Knudsen S, Bassetti C, Mathis J, Lecendreux M, Mayer G, Geisler P, Benetó A, Petit B, Pfister C, Bürki JV, Didelot G, Billiard M, Ercilla G, Verduijn W, Claas FH, Vollenweider P, Waeber G, Waterworth DM, Mooser V, Heinzer R, Beckmann JS, Bergmann S, Tafti M.
Nat Genet. 2010;42(9):786-9.

Elevated Tribbles homolog 2-specific antibody levels in narcolepsy patients.
Cvetkovic-Lopes V, Bayer L, Dorsaz S, Maret S, Pradervand S, Dauvilliers Y, Lecendreux M, Lammers GJ, Donjacour CE, Du Pasquier RA, Pfister C, Petit B, Hor H, Mühlethaler M, Tafti M.
J Clin Invest. 2010 Mar 1;120(3):713-9.

Sodium oxybate is an effective and safe treatment for narcolepsy.
Lammers GJ, Bassetti C, Billiard M, Black J, Broughton R, Dauvilliers Y, Ferini Strambi L, Garcia-Borreguero D, Goswami M, Högl B, Iranzo A, Jennum P, Khatami R, Lecendreux M, Mayer G, Mignot E, Montplaisir J, Nevsimalova S, Peraita-Adrados R, Plazzi G, Scammell T, Silber M, Sonka K, Tafti M, Thorpy M.
Sleep Med. 2010 Jan;11(1):105-6.