Research articles

  • Kesnerova L, Mars RAT, Ellegaard KM, Troilo M, Sauer U, Engel P. Disentangling metabolic functions of bacteria in the honey bee gut. 2017. bioxRiv. [DOI]
  • Emery O, Schmidt K, Engel P. Stimulation of the immune system by the gut symbiont Frischella perrara in the honey bee (Apis mellifera). 2017. Mol Ecol, 26:2576-2590. [DOI][Pubmed]
  • Segers FHID, Kešnerová L, Kosoy M, Engel P. Genomic changes associated with the evolutionary transition of an insect gut commensal into a blood-borne pathogen. 2017. ISME J, 11: 1232–1244.[DOI][Pubmed]
  • Engel P, et al.. The bee microbiome: Impact on bee health and model for evolution and ecology of host-microbe interactions. 2016. mBio, 7(2):e02164-15. [DOI]
  • Kešnerová L, Roxane M, Engel P. Bartonella apis sp. nov., a honey bee gut symbiont of the class Alphaproteobacteria. 2016. IJSEM,66: 414-421. [DOI]
  • Engel P, Bartlett KD, Moran NA. The Bacterium Frischella perrara Causes Scab Formation in the Gut of its Honeybee Host. 2015. mBio, 6(3): e00193-e00115. [DOI]
  • Engel P, Vizcaino MI, Crawford JM. Gut symbionts from distinct hosts exhibit genotoxic activity via divergent colibactin biosynthesis pathways. 2015. AEM,
  • Engel P, Stepanauskas R, Moran NA. Hidden diversity in honey bee gut symbionts detected by single-cell genomics.2014. PLoS Genet, 10(9): e1004596. [DOI]
  • Kwong WK, Engel P, Koch H, Moran NA. Genomics and host specialization of honey bee and bumble bee gut symbionts. 2014. Proc Natl Acad Sci USA, 111(31): 11509-11514. [DOI]
  • Vizcaino MI, Engel P, Trautman E, Crawford JM. Comparative metabolomics and structural characterizations illuminate colibactin pathway-dependent small molecules. 2014. Journal of the American Chemical Society, 136 (26): 9244–9247. [DOI]
  • Engel P, Kwong WK, Moran NA. Frischella perrara gen. nov., sp. nov., a gammaproteobacterium isolated from the gut of the honey bee, Apis mellifera. 2013. IJSEM, 63(10): 3646-3651. [DOI]
  • Engel P, Martinson VG, Moran NA. Functional diversity within the simple gut microbiota of the honey bee. 2012. Proc Natl Acad Sci USA, 109(27):11002-11007. [DOI]
    Press coverage: Science. Editors’ Choice. Microbiology: “Simple But Specific.” 2012, 337 (6091): 134. Caroline Ash.
  • Engel P., Goepfert A*, Stanger FV, Harms A, Schmidt A, Schirmer T, Dehio C. Adenylylation control by intra- or intermolecular active-site obstruction in Fic proteins. 2012. Nature, 482(7383), 107-110. *These authors contributed equally to this work. [DOI]
    Press coverage: Nature Review Microbiology: “Bacterial pathogenesis: Controlling Fic proteins.” 2012, 10 (160). Sheilagh Molloy.
  • Engel P, Salzburger W, Liesch M, Chang CC, Maruyama S, Lanz C, Calteau A, Lajus A, Médigue A, Schuster SC, Dehio C. Parallel evolution of a type IV secretion system in radiating lineages of Bartonella. 2011. PLoS Genet, 7(2): e1001296. [DOI]
  • Vayssier-Taussat M, LeRhun D, Deng H, Biville F, Cescau S, Danchin A, Marignac G, Lenaour E, Boulouis J-H, Mavris M, Arnaud L-M, Yang H-M, Wang J, Quebatte Q, Engel P, Saenz H, Dehio C. The Trw type IV secretion system of Bartonella mediates host-specific infection of erythrocytes. 2010. PLoS Pathog, 6(6):e1000946. [DOI]
  • Quebatte M, Dehio M, Tropel D, Basler A, Toller I, Raddatz G, Engel P, Huser S, Schein H, Lindroos HL, Andersson SGE, Dehio C. The BatR/BatS two component regulatory system controls the adaptive response of Bartonella henselae during human endothelial cell infection. 2010. Journal of Bacteriology, 192(13):3352-67. [DOI]
  • Saenz HL*, Engel P*, Stoeckli MC, Lanz C, Raddatz G, Vayssier-Taussat M, Birtles R, Schuster SC, Dehio C. Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors. 2007. Nature Genetics, 39 (12):1469-1476. *These authors contributed equally to this work. [DOI]


  • Schmidt K, Engel P. Probiotic treatment with a gut symbiont leads to parasite susceptibility in honey bees. 2016. Trends in Parasitology, 32:p914–916. [DOI]
  • Ellegaard KE, Engel P. Beyond 16S rRNA community profiling: Intra-species diversity in the gut microbiota. 2016. Frontiers in Microbiology, 7: 1475. [DOI]
  • Sloan DB, Bennet G, Engel P, Williams D, Ochman H. Disentangling associated genomes. 2013. Methods in Enzymology, 531: 445–464. [DOI]
  • Engel P, James R, Koga R, Kwong WK, McFrederick Q, Moran NA (2013) “Standard methods for research on Apis mellifera gut symbionts.” Journal of Apicultural Research, 52(4), doi: 10.3896/IBRA. [DOI]
  • Engel P, Moran NA (2013) “The gut microbiota of insects – Diversity in structure and function.” FEMS Microbiology Review, 37(5):699-735. [DOI]
    Press coverage: American Society of Microbiology blog: Small Things Considered. Fine Reading: “The gut microbiota of insects – diversity in structure and function.” 2013, Jun 13, Elio Schaechter.
  • Engel P, Moran NA (2012) “Functional and evolutionary insights into the simple yet specific gut microbiota of the honey bee from metagenomic analysis.” Gut Microbes, 4(1): 60–65. [DOI]
  • Engel P, Dehio C (2009) ”Genomics of host-restricted pathogens of the genus Bartonella.” Microbial Pathogenomics, Genome Dynamics, Karger, 6: 158-159. [DOI]