Research articles

  • Ellegaard KM, Engel P. Genomic diversity landscape of the honey bee gut microbiota. Nat Comm. In press.
  • Ellegaard KM, Brochet S, Bonilla-Rosso G, Emery O, Glover N, Hadadi N, Jaron KS, van der Meer JR, Robinson-Rechavi M, Sentchilo V, Tagini F, SAGE class 2016-17, Engel P. Genomic changes underlying host specialization in the bee gut symbiont Lactobacillus Firm5. BioRxiv. [DOI]
  • Jones JC,Fruciano C,Marchant J, Hildebrand F, Forslund S, Bork P, Engel P, Hughes WOH. The gut microbiome is associated with behavioural task in honey bees. 2018. Insectes Sociaux, 65(3): 419-429. [DOI]
  • Hu Y, Sanders JG, Łukasik P, D’Amelio CL, Millar JS, Vann DR, Lan Y, Newton JA, Schotanus M, Kronauer DJC, Pierce NE, Moreau CS, Wertz JT, Engel P, Russell JA. Herbivorous turtle ants obtain essential nutrients from a conserved nitrogen-recycling gut microbiome. 2018. Nat Comm 9 (1): 964. [DOI]
  • Kesnerova L, Mars RAT, Ellegaard KM, Troilo M, Sauer U, Engel P. Disentangling metabolic functions of bacteria in the honey bee gut. 2017. PLoS Biol 15(12): e2003467. [DOI]
  • Tamarit D, Neuvonen M-M, Engel P, Guy L, Andersson SGE. Origin and evolution of the Bartonella gene transfer agent. 2017. Mol Evol Biol, msx299. [DOI|
  • Jones JC, Fruciano C, Hildebrand F, Toufalilia HA, Balfour NJ, Bork P, Engel P, Ratnieks FLW, Hugheset WHO. Gut microbiota composition is associated with environmental landscape in honey bees. Ecol Evol. 2017;00:1–11. [DOI]
  • Harms A, Liesch M, Körner J, Québatte M, Engel P, Dehio C. A bacterial toxin-antitoxin module is the origin of inter-bacterial and inter-kingdom effectors of Bartonella. 2017. PLoS Genet 13: e1007077. [DOI]
  • Emery O, Schmidt K, Engel P. Stimulation of the immune system by the gut symbiont Frischella perrara in the honey bee (Apis mellifera). 2017. Mol Ecol, 26:2576-2590. [DOI][Pubmed]
  • Segers FHID, Kešnerová L, Kosoy M, Engel P. Genomic changes associated with the evolutionary transition of an insect gut commensal into a blood-borne pathogen. 2017. ISME J, 11: 1232–1244.[DOI][Pubmed]
  • Engel P, et al.. The bee microbiome: Impact on bee health and model for evolution and ecology of host-microbe interactions. 2016. mBio, 7(2):e02164-15. [DOI]
  • Kešnerová L, Roxane M, Engel P. Bartonella apis sp. nov., a honey bee gut symbiont of the class Alphaproteobacteria. 2016. IJSEM,66: 414-421. [DOI]
  • Engel P, Bartlett KD, Moran NA. The Bacterium Frischella perrara Causes Scab Formation in the Gut of its Honeybee Host. 2015. mBio, 6(3): e00193-e00115. [DOI]
  • Engel P, Vizcaino MI, Crawford JM. Gut symbionts from distinct hosts exhibit genotoxic activity via divergent colibactin biosynthesis pathways. 2015. AEM,
  • Engel P, Stepanauskas R, Moran NA. Hidden diversity in honey bee gut symbionts detected by single-cell genomics.2014. PLoS Genet, 10(9): e1004596. [DOI]
  • Kwong WK, Engel P, Koch H, Moran NA. Genomics and host specialization of honey bee and bumble bee gut symbionts. 2014. Proc Natl Acad Sci USA, 111(31): 11509-11514. [DOI]
  • Vizcaino MI, Engel P, Trautman E, Crawford JM. Comparative metabolomics and structural characterizations illuminate colibactin pathway-dependent small molecules. 2014. Journal of the American Chemical Society, 136 (26): 9244–9247. [DOI]
  • Engel P, Kwong WK, Moran NA. Frischella perrara gen. nov., sp. nov., a gammaproteobacterium isolated from the gut of the honey bee, Apis mellifera. 2013. IJSEM, 63(10): 3646-3651. [DOI]
  • Engel P, Martinson VG, Moran NA. Functional diversity within the simple gut microbiota of the honey bee. 2012. Proc Natl Acad Sci USA, 109(27):11002-11007. [DOI]
    Press coverage: Science. Editors’ Choice. Microbiology: “Simple But Specific.” 2012, 337 (6091): 134. Caroline Ash.
  • Engel P., Goepfert A*, Stanger FV, Harms A, Schmidt A, Schirmer T, Dehio C. Adenylylation control by intra- or intermolecular active-site obstruction in Fic proteins. 2012. Nature, 482(7383), 107-110. *These authors contributed equally to this work. [DOI]
    Press coverage: Nature Review Microbiology: “Bacterial pathogenesis: Controlling Fic proteins.” 2012, 10 (160). Sheilagh Molloy.
  • Engel P, Salzburger W, Liesch M, Chang CC, Maruyama S, Lanz C, Calteau A, Lajus A, Médigue A, Schuster SC, Dehio C. Parallel evolution of a type IV secretion system in radiating lineages of Bartonella. 2011. PLoS Genet, 7(2): e1001296. [DOI]
  • Vayssier-Taussat M, LeRhun D, Deng H, Biville F, Cescau S, Danchin A, Marignac G, Lenaour E, Boulouis J-H, Mavris M, Arnaud L-M, Yang H-M, Wang J, Quebatte Q, Engel P, Saenz H, Dehio C. The Trw type IV secretion system of Bartonella mediates host-specific infection of erythrocytes. 2010. PLoS Pathog, 6(6):e1000946. [DOI]
  • Quebatte M, Dehio M, Tropel D, Basler A, Toller I, Raddatz G, Engel P, Huser S, Schein H, Lindroos HL, Andersson SGE, Dehio C. The BatR/BatS two component regulatory system controls the adaptive response of Bartonella henselae during human endothelial cell infection. 2010. Journal of Bacteriology, 192(13):3352-67. [DOI]
  • Saenz HL*, Engel P*, Stoeckli MC, Lanz C, Raddatz G, Vayssier-Taussat M, Birtles R, Schuster SC, Dehio C. Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors. 2007. Nature Genetics, 39 (12):1469-1476. *These authors contributed equally to this work. [DOI]


  • Bonilla-Rosso G, Engel P. Functional roles and metabolic niches in the honey bee gut microbiota. 2018. Curr Opin Microbiol, 43:69-76. [DOI]
  • Schmidt K, Engel P. Probiotic treatment with a gut symbiont leads to parasite susceptibility in honey bees. 2016. Trends in Parasitology, 32:p914–916. [DOI]
  • Ellegaard KE, Engel P. Beyond 16S rRNA community profiling: Intra-species diversity in the gut microbiota. 2016. Frontiers in Microbiology, 7: 1475. [DOI]
  • Sloan DB, Bennet G, Engel P, Williams D, Ochman H. Disentangling associated genomes. 2013. Methods in Enzymology, 531: 445–464. [DOI]
  • Engel P, James R, Koga R, Kwong WK, McFrederick Q, Moran NA (2013) “Standard methods for research on Apis mellifera gut symbionts.” Journal of Apicultural Research, 52(4), doi: 10.3896/IBRA. [DOI]
  • Engel P, Moran NA (2013) “The gut microbiota of insects – Diversity in structure and function.” FEMS Microbiology Review, 37(5):699-735. [DOI]
    Press coverage: American Society of Microbiology blog: Small Things Considered. Fine Reading: “The gut microbiota of insects – diversity in structure and function.” 2013, Jun 13, Elio Schaechter.
  • Engel P, Moran NA (2012) “Functional and evolutionary insights into the simple yet specific gut microbiota of the honey bee from metagenomic analysis.” Gut Microbes, 4(1): 60–65. [DOI]
  • Engel P, Dehio C (2009) ”Genomics of host-restricted pathogens of the genus Bartonella.” Microbial Pathogenomics, Genome Dynamics, Karger, 6: 158-159. [DOI]